phosphoinositidase C

Known as: Phosphatidylinositol Phospholipase C, PLC-Gamma-1, Triphosphoinositide Phosphodiesterase 
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 (1290 aa, ~149 kDa) is encoded by the human PLCG1 gene. This protein is involved in… (More)
National Institutes of Health

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Highly Cited
2006
Highly Cited
2006
The Abl family of nonreceptor tyrosine kinases consists of two related proteins, c-Abl and Abl-related gene (Arg). Activated… (More)
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Highly Cited
2002
Highly Cited
2002
Hyaluronan (HA) is a large nonsulfated glycosaminoglycan and an important regulator of angiogenesis, in particular, the growth… (More)
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Highly Cited
2002
Highly Cited
2002
Microinjection in mouse eggs of tr-kit, a truncated form of the c-kit tyrosine kinase present in mouse spermatozoa, causes… (More)
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Highly Cited
2001
Highly Cited
2001
T-cell-receptor (TCR)-mediated LAT (linker for activation of T cells) phosphorylation is critical for the membrane recruitment of… (More)
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Highly Cited
2001
Highly Cited
2001
The hematopoietic cell-specific protein Vav1 is a substrate of tyrosine kinases activated following engagement of many receptors… (More)
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Review
1993
Review
1993
Five adrenoceptor subtypes are involved in the adrenergic regulation of white and brown fat cell function. The effects on cAMP… (More)
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1993
1993
The presence of phosphoinositide-mobilizing enzymes has been investigated in purified rat liver nuclei by radiolabelling and by… (More)
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Highly Cited
1992
Highly Cited
1992
THE hydrolysis of phosphatidylinositol 4,5-bisphosphate (PtdInsP2) is a widespread receptor-coupled signalling system at the… (More)
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Highly Cited
1992
Highly Cited
1992
The ether lipid analogue 1-octadecyl-2-methyl-rac-glycero-3-phosphocholine (ET-18-OCH3) has been shown to be a direct inhibitor… (More)
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Highly Cited
1988
Highly Cited
1988
The production of the second messenger molecules diacylglycerol and inositol 1,4,5-trisphosphate1 is mediated by activated phos… (More)
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