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phosphatidylinositol phospholipase C activity

Known as: 1-phosphatidyl-1D-myo-inositol-4,5-bisphosphate inositoltrisphosphohydrolase activity, PI-PLC activity, 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase activity 
Catalysis of the reaction: 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate + H(2)O = 1,2-diacylglycerol + 1D-myo-inositol 1,4,5-trisphosphate + H… Expand
National Institutes of Health

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Rat liver cells were homogenized and subsequently fractionated by a simplified method based on microfiltration, which proved to… Expand
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