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phosphatidylinositol metabolic process

Known as: phosphatidylinositol metabolism, PtdIns metabolic process, PtdIns metabolism 
The chemical reactions and pathways involving phosphatidylinositol, any glycophospholipid in which a sn-glycerol 3-phosphate residue is esterified to… Expand
National Institutes of Health

Papers overview

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Highly Cited
2011
Highly Cited
2011
Osh4p exchanges sterols for phosphatidylinositol 4-phosphate between lipid bilayers
The yeast Kes1p/Osh4p protein functions as a sterol/PI(4)P exchanger between lipid membranes, which suggests the possibility of… Expand
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Review
2004
Review
2004
Protein-lipid interactions and phosphoinositide metabolism in membrane traffic: insights from vesicle recycling in nerve terminals.
Great progress has been made in the elucidation of the function of proteins in membrane traffic. Less is known about the… Expand
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Highly Cited
2003
Highly Cited
2003
Phosphoinositide profiling in complex lipid mixtures using electrospray ionization mass spectrometry
Phosphoinositides (phosphorylated derivatives of phosphatidylinositol, PI) are versatile intracellular signaling lipids whose… Expand
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Review
2001
Review
2001
Phosphoinositides in membrane traffic at the synapse.
Inositol phospholipids represent a minor fraction of membrane phospholipids; yet they play important regulatory functions in… Expand
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Highly Cited
1999
Highly Cited
1999
Essential Role of Phosphoinositide Metabolism in Synaptic Vesicle Recycling
Growing evidence suggests that phosphoinositides play an important role in membrane traffic. A polyphosphoinositide phosphatase… Expand
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Highly Cited
1996
Highly Cited
1996
A presynaptic inositol-5-phosphatase
SYNAPTOJANIN is a nerve terminal protein of relative molecular mass 145,000 which appears to participate with dynamin in synaptic… Expand
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Highly Cited
1993
Highly Cited
1993
Mechanisms by which glucose can control insulin release independently from its action on adenosine triphosphate-sensitive K+ channels in mouse B cells.
Glucose stimulation of insulin release involves closure of ATP-sensitive K+ channels (K(+)-ATP channels), depolarization, and Ca2… Expand
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Highly Cited
1990
Highly Cited
1990
Regions of the alpha 1-adrenergic receptor involved in coupling to phosphatidylinositol hydrolysis and enhanced sensitivity of biological function.
Regions of the hamster alpha 1-adrenergic receptor (alpha 1 AR) that are important in GTP-binding protein (G protein)-mediated… Expand
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Highly Cited
1982
Highly Cited
1982
Lithium amplifies agonist-dependent phosphatidylinositol responses in brain and salivary glands.
1. The effect of Li+ on the agonist-dependent metabolism of [3H]inositol has been studied in rat brain, rat parotid and the… Expand
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Highly Cited
1979
Highly Cited
1979
Hormonal stimulation of phosphatidylinositol breakdown with particular reference to the hepatic effects of vasopressin.
Stimulated phosphatidylinositol breakdown, followed by compensatory resynthesis, is a response of a wide variety of cells to many… Expand
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