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phosphatidylinositol metabolic process

Known as: phosphatidylinositol metabolism, PtdIns metabolic process, PtdIns metabolism 
The chemical reactions and pathways involving phosphatidylinositol, any glycophospholipid in which a sn-glycerol 3-phosphate residue is esterified to… 
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2011
Highly Cited
2011
Osh4p exchanges sterols for phosphatidylinositol 4-phosphate between lipid bilayers
The yeast Kes1p/Osh4p protein functions as a sterol/PI(4)P exchanger between lipid membranes, which suggests the possibility of… 
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Review
2005
Review
2005
AKT signaling in normal and malignant cells
AKT/protein kinase B (PKB) is a cardinal node in diverse signaling cascades important in both normal cellular physiology and… 
Review
2004
Review
2004
Protein-lipid interactions and phosphoinositide metabolism in membrane traffic: insights from vesicle recycling in nerve terminals.
Great progress has been made in the elucidation of the function of proteins in membrane traffic. Less is known about the… 
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Review
2001
Review
2001
Phosphoinositides in membrane traffic at the synapse.
Inositol phospholipids represent a minor fraction of membrane phospholipids; yet they play important regulatory functions in… 
Highly Cited
1999
Highly Cited
1999
Essential Role of Phosphoinositide Metabolism in Synaptic Vesicle Recycling
Growing evidence suggests that phosphoinositides play an important role in membrane traffic. A polyphosphoinositide phosphatase… 
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Highly Cited
1996
Highly Cited
1996
A presynaptic inositol-5-phosphatase
SYNAPTOJANIN is a nerve terminal protein of relative molecular mass 145,000 which appears to participate with dynamin in synaptic… 
Highly Cited
1993
Highly Cited
1993
Mechanisms by which glucose can control insulin release independently from its action on adenosine triphosphate-sensitive K+ channels in mouse B cells.
Glucose stimulation of insulin release involves closure of ATP-sensitive K+ channels (K(+)-ATP channels), depolarization, and Ca2… 
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Highly Cited
1990
Highly Cited
1990
Regions of the alpha 1-adrenergic receptor involved in coupling to phosphatidylinositol hydrolysis and enhanced sensitivity of biological function.
Regions of the hamster alpha 1-adrenergic receptor (alpha 1 AR) that are important in GTP-binding protein (G protein)-mediated… 
Highly Cited
1982
Highly Cited
1982
Lithium amplifies agonist-dependent phosphatidylinositol responses in brain and salivary glands.
1. The effect of Li+ on the agonist-dependent metabolism of [3H]inositol has been studied in rat brain, rat parotid and the… 
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Highly Cited
1979
Highly Cited
1979
Hormonal stimulation of phosphatidylinositol breakdown with particular reference to the hepatic effects of vasopressin.
Stimulated phosphatidylinositol breakdown, followed by compensatory resynthesis, is a response of a wide variety of cells to many… 
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