phosphatidylinositol alpha-mannosyltransferase activity

Known as: phosphatidyl-myo-inositol alpha-mannosyltransferase activity, GDP mannose-phosphatidyl-myo-inositol alpha-mannosyltransferase activity, GDP mannose:1-phosphatidyl-myo-inositol alpha-D-mannosyltransferase activity 
Catalysis of the transfer of one or more alpha-D-mannose residues from GDP-mannose to positions 2,6 and others in 1-phosphatidyl-myo-inositol. [EC:2… (More)
National Institutes of Health

Papers overview

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Review
2017
Review
2017
Insights into Interactions of Mycobacteria with the Host Innate Immune System from a Novel Array of Synthetic Mycobacterial Glycans
An array of homogeneous glycans representing all the major carbohydrate structures present in the cell wall of the human pathogen… (More)
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2014
2014
The phosphatidyl-myo-inositol mannosyltransferase PimA is essential for Mycobacterium tuberculosis growth in vitro and in vivo.
The cell envelope of Mycobacterium tuberculosis contains glycans and lipids of peculiar structure that play prominent roles in… (More)
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Review
2010
Review
2010
Molecular basis of phosphatidyl-myo-inositol mannoside biosynthesis and regulation in mycobacteria.
Phosphatidyl-myo-inositol mannosides (PIMs) are unique glycolipids found in abundant quantities in the inner and outer membranes… (More)
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2004
2004
In vivo molecular pharmacology and antitumor activity of the targeted Akt inhibitor PX-316.
Akt, a serine/threonine kinase that promotes cell survival, is activated by binding of its pleckstrin homology (PH) domain to… (More)
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2004
2004
Acid sphingomyelinase and inhibition by phosphate ion: role of inhibition by phosphatidyl-myo-inositol 3,4,5-triphosphate in oligodendrocyte cell signaling.
There is ample evidence that both acid (ASMase) and neutral (NSMase) sphingomyelinases play a role in cell death so inhibitors of… (More)
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2003
2003
Specific inhibition of the Akt1 pleckstrin homology domain by D-3-deoxy-phosphatidyl-myo-inositol analogues.
Activation of Akt (protein kinase B), a Ser/Thr protein kinase that promotes cell survival, has been linked to tumorigenesis. Akt… (More)
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2001
2001
Two unusual glycerophospholipids from a filamentous fungus, Absidia corymbifera.
The chloroform-methanol extractable lipids of the soil filamentous fungus Absidia corymbifera VKMF-965 account for about 20% by… (More)
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1994
1994
Synthesis of acylphosphonyl analogues of phosphatidyl-myo-inositol as inhibitors of phosphatidylinositol-specific phospholipase C.
 
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1978
1978
Studies on the properties of triphosphoinositide phosphomonoesterase and phosphodiesterase of rabbit iris smooth muscle.
The rabbit iris smooth muscle has been shown to contain triphosphoinositide phosphomonoesterase (phosphatidyl-myo-inositol-4,5… (More)
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1965
1965
Biosynthesis of diphosphoinositide in brain.
In 1942, Folch and Woolley (1) reported that inositol is a constituent of brain phospholipids. Folch (2) later isolated from… (More)
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