phosphatidylinositol 3-kinase complex, class IA

Known as: class IA PI3K complex, phosphatidylinositol 3-kinase complex location, class IA, phosphoinositide 3-kinase complex, class IA 
A class I phosphatidylinositol 3-kinase complex that possesses 1-phosphatidylinositol-4-phosphate 3-kinase activity; comprises a catalytic class IA… (More)
National Institutes of Health

Papers overview

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2010
2010
Autophagy is an evolutionarily conserved cell renewal process that depends on phosphatidylinositol 3-phosphate (PtdIns(3)P). In… (More)
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2009
2009
Acquisition of a transformed phenotype involves deregulation of several signal transduction pathways contributing to… (More)
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Highly Cited
2008
Highly Cited
2008
Nephrin is a slit diaphragm protein critical for structural and functional integrity of visceral glomerular epithelial cells… (More)
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2008
2008
The PIK3CA gene, encoding the p110alpha catalytic subunit of Class IA PI3Ks (phosphoinositide 3-kinases), is frequently mutated… (More)
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2003
2003
Background—We have recently shown that genetic inactivation of phosphoinositide 3-kinase (PI3K ), the isoform linked to G-protein… (More)
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Highly Cited
2002
Highly Cited
2002
Many receptor and nonreceptor tyrosine kinases activate phosphoinositide 3-kinases (PI3Ks). To assess the role of the delta… (More)
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Highly Cited
2002
Highly Cited
2002
Endothelial nitric-oxide synthase (eNOS) is an important component of vascular homeostasis. During vascular disease, endothelial… (More)
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2002
2002
Phosphoinositide 3-kinase (PI3-kinase)-dependent phosphorylation of the proapoptotic Bcl-2 family member Bad has been proposed as… (More)
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2001
2001
Multiple signal transduction events are triggered in the host cell during invasion by the protozoan parasite Trypanosoma cruzi… (More)
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1998
1998
ErbB3 (HER3), a unique member of the ErbB receptor family, lacks intrinsic protein tyrosine kinase activity and contains six Tyr… (More)
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