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phosphatidylinositol 3-kinase activity

Known as: phosphoinositide 3-kinase activity 
Catalysis of the reaction: ATP + a phosphatidylinositol = ADP + a phosphatidylinositol 3-phosphate. This reaction is the addition of a phosphate… 
National Institutes of Health

Related topics

Related topics

5 relations
PIK3C2A genePIK3C2B genePIK3C2G genePIK3C3 gene

Broader (1)

phosphatidylinositol phosphorylation

Papers overview

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2012
2012
p85β increases phosphoinositide 3-kinase activity and accelerates tumor progression
Comment on: Cortés I, et al. Proc Natl Acad Sci USA 2012; 109:11318-23. 
2009
2009
In Vivo Knockdown of p85α with an Antisense Oligonucleotide Improves Insulin Sensitivity in Lep ob/ob and Diet-induced Obese Mice
In vivo 
2006
2006
ANG II enhances contractile responses via PI 3-kinase p 110 pathway in aortas from diabetic rats with systemic hyperinsulinemia
Kobayashi, Tsuneo, Yuko Hayashi, Kumiko Taguchi, Takayuki Matsumoto, and Katsuo Kamata. ANG II enhances contractile responses via… 
2005
2005
Cyclic AMP inhibition of proliferation of hepatocellular carcinoma cells Is mediated by Akt
Cyclic AMP (cAMP), one of the most important intracellular second messengers, has been reported to inhibit proliferation of human… 
2003
2003
Regulation of retinal phosphoinositide 3-kinase activity in p85alpha-subunit knockout mice.
A variety of growth factors and hormones mediate their cellular affects via interactions with cell surface receptors that possess… 
2003
2003
Leptin regulated insulin secretion via stimulating IRS2-associated phosphoinositide 3-kinase activity in the isolated rat pancreatic islets
SummaryTo investigate the molecular mechanism of leptin regulating insulin secretion through determining the regulation of… 
2000
2000
Measurement of phosphoinositide 3-kinase activity.
  • S. Ward
  • Methods in molecular biology
  • 2000
  • Corpus ID: 35164938
1999
1999
Islet transplantation restores normal levels of insulin receptor and substrate tyrosine phosphorylation and phosphatidylinositol 3-kinase activity in skeletal muscle and myocardium of streptozocin…
Insulin-dependent diabetes in rats is characterized by abnormalities of post-binding insulin signaling reactions that are not… 
1995
1995
EFFECT OF LOVASTATIN AND FLUOROMEVALONATE ON PHOSPHATIDYLINOSITOL 3‐KINASE ACTIVITY STIMULATED WITH PDGF
1. Phosphatidylinositol 3‐kinase (PI3K) appears to have a crucial role in cellular proliferation induced by platelet‐derived… 
1995
1995
Effect of phorbol esters on phosphatidylinositol 3-kinase activity in adipocytes.
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