phosphatase inhibitor

 
National Institutes of Health

Topic mentions per year

Topic mentions per year

1952-2017
05019522016

Papers overview

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Highly Cited
2009
Highly Cited
2009
Ataxia telangiectasia (A-T) mutated (ATM) is critical for cell cycle checkpoints and DNA repair. Thus, specific small molecule… (More)
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Highly Cited
2008
Highly Cited
2008
Pyrophosphate is a potent inhibitor of medial vascular calcification where its level is controlled by hydrolysis via a tissue… (More)
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Highly Cited
2008
Highly Cited
2008
Superoxide dismutase 1 (SOD1) is an abundant copper/zinc enzyme found in the cytoplasm that converts superoxide into hydrogen… (More)
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2006
2006
Protein phosphatases have very recently emerged as important targets for chemical biology and medicinal chemistry research, and… (More)
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Highly Cited
2004
Highly Cited
2004
Affinity isolation of protein serine/threonine phosphatases on the immobilized phosphatase inhibitor microcystin-LR identified… (More)
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Highly Cited
2001
Highly Cited
2001
Action of protein kinases and phosphatases contributes to myocardial hypertrophy. PRL-3, a protein tyrosine phosphatase, was… (More)
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Highly Cited
1996
Highly Cited
1996
c-Jun N-terminal kinases (JNKs) participate in cellular responses to mitogenic stimuli, environmental stresses, and apoptotic… (More)
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Highly Cited
1995
Highly Cited
1995
The antiapoptosis potential of Bcl-2 protein is well established, but the mechanism of Bcl-2 action is still poorly understood… (More)
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Highly Cited
1994
Highly Cited
1994
Protein kinases modulate the activity of several ligand-gated ion channels, including the NMDA (N-methyl-D-aspartate) subtype of… (More)
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Highly Cited
1991
Highly Cited
1991
Okadaic acid, a specific and potent inhibitor of protein phosphatases 2A and 1, was tested for its effect on the morphology of a… (More)
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