Semantic Scholar uses AI to extract papers important to this topic.
We describe here the pharmacological properties of RP 67580 [(3aR,7aR)-7,7-diphenyl-2-[1-imino-2-(2-methoxyphenyl)ethyl… Expand DuP 697 (5-bromo-2[4-fluorophenyl]-3-[4-methylsulfonylphenyl]-thiophene) is a potent inhibitor of paw swelling in nonestablished… Expand The antinociceptive potency of morphine as determined by the tail-flick test was significantly decreased in streptozotocin (STZ… Expand Clonidine was found to possess dose-dependent analgesic and antiwithdrawal activity. In mice, clonidine prolonged the tail flick… Expand Relative pharmacological potencies of the optical isomers of ketamine have been estimated in ICR mice. The (+)-isomer was 3X more… Expand The objective of this study was to characterize further the nature of nitrous oxide analgesia and to establish if tolerance to… Expand Nitrous oxide produced a dose-related "analgesia" in mice (median effective dose, 55 percent). The analgesia was evaluated by… Expand Antinociceptive activity of intraventricularly administered acetylcholine was quantitated in mice by the tail-flick and… Expand We have investigated the effect of a number of agents which alter central neurohumeral tone on the activity of morphine and the… Expand The frequency of writhing motions in mice given phenylquinone intraperitoneally can be altered by low doses of Na… Expand