phenylalanyl-prolyl-arginine-chloromethyl ketone

Known as: PPACK, phenylalanyl-prolyl-arginyl-chloromethane, FPRCK 
 
National Institutes of Health

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Highly Cited
2008
Highly Cited
2008
Plasmids To construct the miR-29b/c-enhancer-Luc-wt reporter plasmid, a ~ 4.5 kb fragment containing the YY1 D site along with… (More)
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2006
2006
BACKGROUND Fibrinogen (Fg) has been considered essential for platelet aggregation. However, we recently demonstrated formation of… (More)
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Highly Cited
2001
Highly Cited
2001
The activation of human platelets by alpha-thrombin is mediated at least in part by cleavage of protease-activated G-protein… (More)
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Highly Cited
1997
Highly Cited
1997
BACKGROUND Integrilin (eptifibatide), a potent inhibitor of the fibrinogen binding function of GP IIb-llla, has been shown to… (More)
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Highly Cited
1996
Highly Cited
1996
Platelet-derived microparticles (MP) are reported to express both pro- and anticoagulant activities. Nevertheless, their… (More)
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1995
1995
We recently devised three-colour flow cytometric assay for evaluating expression of CD11b on neutrophils and monocytes in… (More)
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Highly Cited
1991
Highly Cited
1991
Recent studies have revealed a role for platelets and the platelet-adhesive proteins, fibronectin and von Willebrand factor (vWF… (More)
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1991
1991
The mode of binding of four active-site directed inhibitors to human thrombin has been determined by x-ray crystallographic… (More)
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Highly Cited
1990
Highly Cited
1990
Propagation of venous thrombi or rethrombosis after coronary thrombolytic therapy can occur despite heparin administration. To… (More)
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1986
1986
Competition binding studies have been carried out to evaluate the antagonism of TLCK-thrombin (N alpha-tosyl-L-lysine… (More)
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