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phenyl methimazole
Known as:
phenylmethimazole
National Institutes of Health
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Related topics
Related topics
3 relations
Broader (2)
Methimazole
Thiones
analogs & derivatives
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2017
2017
Phenylmethimazole and a thiazole derivative of phenylmethimazole inhibit IL‐6 expression by triple negative breast cancer cells
Mahboubeh S. Noori
,
John D. O'Brien
,
+8 authors
D. J. Goetz
European journal of pharmacology
2017
Corpus ID: 19370760
2017
2017
TLR signaling inhibitor, phenylmethimazole, in combination with tamoxifen inhibits human breast cancer cell viability and migration
A. Schwartz
,
E. Dickerson
,
N. Dagia
,
R. Malgor
,
Kelly D. Mccall
Oncotarget
2017
Corpus ID: 9044755
Heightened co-expression and dysregulated signaling associated with Toll-like receptor 3 (TLR3) and Wnt5a is an integral…
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2013
2013
Phenylmethimazole Suppresses dsRNA-Induced Cytotoxicity and Inflammatory Cytokines in Murine Pancreatic Beta Cells and Blocks Viral Acceleration of Type 1 Diabetes in NOD Mice
Kelly D. Mccall
,
M. Schmerr
,
+5 authors
F. Schwartz
Molecules
2013
Corpus ID: 15034613
Accumulating evidence supports a role for viruses in the pathogenesis of type 1 diabetes mellitus (T1DM). Activation of dsRNA…
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2012
2012
Phenylmethimazole Blocks dsRNA-Induced IRF3 Nuclear Translocation and Homodimerization
M. Courreges
,
Noriko Kantake
,
D. J. Goetz
,
F. Schwartz
,
Kelly D. Mccall
Molecules
2012
Corpus ID: 10711183
Previous studies revealed that phenylmethimazole (C10) inhibits IRF3 signaling, preventing dsRNA-induction of type 1 interferon…
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Highly Cited
2010
Highly Cited
2010
Phenylmethimazole blocks palmitate-mediated induction of inflammatory cytokine pathways in 3T3L1 adipocytes and RAW 264.7 macrophages.
Kelly D. Mccall
,
D. Holliday
,
+6 authors
F. Schwartz
The Journal of endocrinology
2010
Corpus ID: 24745033
Visceral adipocytes and associated macrophages produce and release excessive amounts of biologically active inflammatory…
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2010
2010
Regulation of major histocompatibility complex gene expression in thyroid epithelial cells by methimazole and phenylmethimazole.
C. Giuliani
,
I. Bucci
,
+4 authors
G. Napolitano
The Journal of endocrinology
2010
Corpus ID: 21113204
Increased expression of major histocompatibility complex (MHC) class-I genes and aberrant expression of MHC class-II genes in…
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Highly Cited
2009
Highly Cited
2009
Phenylmethimazole Decreases Toll-Like Receptor 3 and Noncanonical Wnt5a Expression in Pancreatic Cancer and Melanoma Together with Tumor Cell Growth and Migration
A. Schwartz
,
R. Malgor
,
+10 authors
Kelly D. Mccall
Clinical Cancer Research
2009
Corpus ID: 13797476
Purpose: To evaluate whether (a) Wnt5a expression in pancreatic cancer and malignant melanoma cells might be associated with…
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Highly Cited
2007
Highly Cited
2007
High basal levels of functional toll-like receptor 3 (TLR3) and noncanonical Wnt5a are expressed in papillary thyroid cancer and are coordinately decreased by phenylmethimazole together with cell…
Kelly D. Mccall
,
N. Harii
,
+6 authors
L. Kohn
Endocrinology
2007
Corpus ID: 5765206
High basal levels of TLR3 and Wnt5a RNA are present in papillary thyroid carcinoma (PTC) cell lines consistent with their…
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Highly Cited
2005
Highly Cited
2005
Thyrocytes express a functional toll-like receptor 3: overexpression can be induced by viral infection and reversed by phenylmethimazole and is associated with Hashimoto's autoimmune thyroiditis.
N. Harii
,
C. Lewis
,
+9 authors
L. Kohn
Molecular endocrinology
2005
Corpus ID: 19146387
Toll-like receptors (TLRs) initiate an innate immune response. TLR3 on dendritic cells recognize double-stranded (ds) RNA and…
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Highly Cited
2004
Highly Cited
2004
Phenyl Methimazole Inhibits TNF-α-Induced VCAM-1 Expression in an IFN Regulatory Factor-1-Dependent Manner and Reduces Monocytic Cell Adhesion to Endothelial Cells1
N. Dagia
,
N. Harii
,
+4 authors
D. J. Goetz
The Journal of Immunology
2004
Corpus ID: 38188148
Proinflammatory cytokine (e.g., TNF-α)-induced expression of endothelial cell adhesion molecules (ECAMs) on the lumenal surface…
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