phensuximide

The in vivo metabolism in humans of the anticonvulsant mephenytoin exhibits stereoselectivity as well as genetic polymorphism of… Expand

Teratogenicity tests should provide answers to three questions: (1) Can the agent induce developmental defects? ("teratogenic… Expand

Because acute attacks of porphyria may be precipitated by anticonvulsants, a therapeutic dilemma arises when seizures complicate… Expand

Nitrosourea derivatives 9--13 which utilize phensuximide (1) as the carrier were synthesized as potential central nervous system… Expand

The clinical efficacy of phensuximide and methsuximide was studied in relation to plasma concentrations of these compounds and… Expand

Veratridine causes deplorization of excitable cells and produces marked elevation of adenosine 3',5'-monophosphate (cyclic AMP… Expand

 

Ethosuximide and phensuximide in plasma and urine can be assayed to a concentration of 2–5 μg ml−1 by a rapid and specific gas… Expand

SUMMARY The anticonvulsant properties and toxicity of phensuximide (Milontin), methsuximide (Celontin) and ethosuximide… Expand

THIS STUDY deals with the effectiveness of ethosuximide (Zarontin) in the treatment of 100 patients with recurrent, short, mild… Expand