phensuximide

The in vivo metabolism in humans of the anticonvulsant mephenytoin exhibits stereoselectivity as well as genetic polymorphism of… Expand

Phensuximide is a succinimide antiepileptic drug useful in the treatment of petit mal epilepsy. Phensuximide has been reported to… Expand

Teratogenicity tests should provide answers to three questions: (1) Can the agent induce developmental defects? ("teratogenic… Expand

Because acute attacks of porphyria may be precipitated by anticonvulsants, a therapeutic dilemma arises when seizures complicate… Expand

Nitrosourea derivatives 9--13 which utilize phensuximide (1) as the carrier were synthesized as potential central nervous system… Expand

Ethosuximide and phensuximide in plasma and urine can be assayed to a concentration of 2–5 μg ml−1 by a rapid and specific gas… Expand

After oral administration of racemic (RS) phensuximide ( 1 ) to dogs, compounds found in urine (with approximate yields as… Expand

Abstract Phenobarbital, diphenylhydantoin, primidone, methoin, phensuximide, methsuximide, mephobarbital, heptabarbital… Expand

The anticonvulsant properties and toxicity of phensuximide (Milontin), methsuximide (Celontin) and ethosuximide (Zarontin) have… Expand

THIS STUDY deals with the effectiveness of ethosuximide (Zarontin) in the treatment of 100 patients with recurrent, short, mild… Expand