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phensuximide
Known as:
Fensuximida
, Phensuximidum
, Fensuccimide
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National Institutes of Health
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Related topics
Related topics
4 relations
Childhood Absence Epilepsy
Drug Allergy
Neurotransmitter & Neuromuscular Transmitter Activity Alteration [PE]
Broader (1)
Succinimides
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
1987
Highly Cited
1987
Characterization and inhibition of mephenytoin 4-hydroxylase activity in human liver microsomes.
S. Hall
,
F. Guengerich
,
R. Branch
,
G. Wilkinson
The Journal of pharmacology and experimental…
1987
Corpus ID: 19377241
The in vivo metabolism in humans of the anticonvulsant mephenytoin exhibits stereoselectivity as well as genetic polymorphism of…
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Highly Cited
1982
Highly Cited
1982
The relative teratogenic index and teratogenic potency: proposed components of developmental toxicity risk assessment.
S. Fabro
,
G. Shull
,
N. Brown
Teratogenesis, carcinogenesis, and mutagenesis
1982
Corpus ID: 249933
Teratogenicity tests should provide answers to three questions: (1) Can the agent induce developmental defects? ("teratogenic…
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Highly Cited
1981
Highly Cited
1981
Safety of anticonvulsants in hepatic porphyrias
N. Reynolds
,
R. M. Miska
Neurology
1981
Corpus ID: 40044726
Because acute attacks of porphyria may be precipitated by anticonvulsants, a therapeutic dilemma arises when seizures complicate…
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Highly Cited
1980
Highly Cited
1980
Synthesis and anticancer activity of nitrosourea derivatives of phensuximide.
A. Crider
,
T. M. Kolczynski
,
K. Yates
Journal of medicinal chemistry
1980
Corpus ID: 1790966
Nitrosourea derivatives 9--13 which utilize phensuximide (1) as the carrier were synthesized as potential central nervous system…
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Review
1980
Review
1980
Clinical pharmacokinetics of antiepileptic drugs in adults.
P. Morselli
,
R. Franco-Morselli
Pharmacology & therapeutics
1980
Corpus ID: 33947867
1973
1973
A rapid method for the estimation of anti-epileptic drugs in blood serum by gas-liquid chromatography.
H. M. Cremers
,
P. E. Verheesen
Clinica chimica acta; international journal of…
1973
Corpus ID: 42044737
1973
1973
Gas chromatographic determination of ethosuximide and phensuximide in plasma and urine of man
E. Kleijn
,
P. Collste
,
B. Norlander
,
S. Agurell
,
F. Sjöqvist
The Journal of pharmacy and pharmacology
1973
Corpus ID: 30870202
Ethosuximide and phensuximide in plasma and urine can be assayed to a concentration of 2–5 μg ml−1 by a rapid and specific gas…
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Highly Cited
1966
Highly Cited
1966
The estimation of some important anticonvulsant drugs in serum.
J. Huisman
Clinica chimica acta; international journal of…
1966
Corpus ID: 38252453
Highly Cited
1963
Highly Cited
1963
Anticonvulsant Activity and Toxicity of Phensuximide, Methsuximide and Ethosuximide
G. Chen
,
J. K. Weston
,
A. C. Bratton
Epilepsia
1963
Corpus ID: 29675349
The anticonvulsant properties and toxicity of phensuximide (Milontin), methsuximide (Celontin) and ethosuximide (Zarontin) have…
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Highly Cited
1962
Highly Cited
1962
Ethosuximide in the treatment of epilepsy.
E. Goldensohn
,
J. Hardie
,
E. Borea
JAMA
1962
Corpus ID: 44779606
THIS STUDY deals with the effectiveness of ethosuximide (Zarontin) in the treatment of 100 patients with recurrent, short, mild…
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