phenserine

Known as: (-)-phenserine, (-)-eseroline phenylcarbamate, N-phenylcarbamoyleseroline 
 
National Institutes of Health

Topic mentions per year

Topic mentions per year

1993-2018
02419932018

Papers overview

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2010
2010
To gather preliminary evidence in Alzheimer's disease (AD) for the efficacy of phenserine, a non-competitive acetylcholinesterase… (More)
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2008
2008
OBJECTIVE The effects of (-)-phenserine (phenserine) and placebo/donepezil treatment on regional cerebral metabolic rate for… (More)
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2007
2007
In a previous study, we found that human neural stem cells (HNSCs) exposed to high concentrations of secreted amyloid-precursor… (More)
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2007
2007
Major characteristics of Alzheimer's disease (AD) are synaptic loss, cholinergic dysfunction, and abnormal protein depositions in… (More)
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2005
2005
Male Fischer-344 rats (n = 38) at 5 months old were tested in a Morris water maze to determine if treatment with the… (More)
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2005
2005
OBJECTIVE To evaluate the safety, maximum tolerated dose (MTD), pharmacokinetics (PK), and pharmacodynamics (PD) of the acetyl… (More)
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2004
2004
The Alzheimer's amyloid precursor protein (APP) is the metalloprotein that is cleaved to generate the pathogenic Abeta peptide… (More)
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2001
2001
The reduction in levels of the potentially toxic amyloid-beta peptide (Abeta) has emerged as one of the most important… (More)
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1999
1999
Four novel analogues (8-11) of cymserine (2) were synthesized by methods similar to those recently developed for the total… (More)
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1995
1995
A new generation of cholinesterase inhibitors is expected to overcome some limitations of the therapeutic use of… (More)
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