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peroxiredoxin IV

Known as: Peroxiredoxin 4, Peroxiredoxin-4 
National Institutes of Health

Related topics

Related topics

3 relations
PRDX4 gene

Narrower (1)

PRDX4 protein, human

Broader (1)

thioredoxin peroxidase

Papers overview

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Highly Cited
2017
Highly Cited
2017
Peroxiredoxin 4 inhibits IL-1β-induced chondrocyte apoptosis via PI3K/AKT signaling.
Highly Cited
2014
Highly Cited
2014
Peroxiredoxin 4 Improves Insulin Biosynthesis and Glucose-induced Insulin Secretion in Insulin-secreting INS-1E Cells*
Background: Peroxiredoxin 4 facilitates de novo disulfide bond formation by metabolizing hydrogen peroxide. Results… 
2014
2014
High expression of peroxiredoxin 4 affects the survival time of colorectal cancer patients, but is not an independent unfavorable prognostic factor.
Peroxiredoxin 4 (Prx4) has a number of important biological functions, such as efficient antioxidant capacity and promotion of… 
Highly Cited
2013
Highly Cited
2013
Peroxiredoxin 4 protects against nonalcoholic steatohepatitis and type 2 diabetes in a nongenetic mouse model.
AIMS Consumption of a high-fructose diet (HFrD) can induce the development of a metabolic syndrome, manifesting as nonalcoholic… 
Highly Cited
2013
Highly Cited
2013
Dynamic Regulation of Ero1α and Peroxiredoxin 4 Localization in the Secretory Pathway*
Background: Ero1α and peroxiredoxin 4 contribute to disulfide formation in the early secretory compartment (ESC), but lack known… 
2013
2013
The effect of peroxiredoxin 4 on fly physiology is a complex interplay of antioxidant and signaling functions
Peroxiredoxin 4 (Prx4) has been implicated in a wide variety of biological processes, including development, progression of… 
Highly Cited
2012
Highly Cited
2012
Suppression of Peroxiredoxin 4 in Glioblastoma Cells Increases Apoptosis and Reduces Tumor Growth
Glioblastoma multiforme (GBM), the most common and aggressive primary brain malignancy, is incurable despite the best combination… 
Highly Cited
2012
Highly Cited
2012
Overexpression of peroxiredoxin 4 attenuates atherosclerosis in apolipoprotein E knockout mice.
AIM A growing body of evidence has shown that increased formation of oxidized molecules and reactive oxygen species within the… 
2012
2012
Peroxiredoxin 4, A Novel Circulating Biomarker for Oxidative Stress and the Risk of Incident Cardiovascular Disease and All-Cause Mortality
Background Oxidative stress has been suggested to play a key role in the development of cardiovascular disease (CVD). The aim of… 
2011
2011
Is overoxidation of peroxiredoxin physiologically significant?
Eukaryotic peroxiredoxins are highly susceptible to sulfinic acid formation. This overoxidation, which is thought to convert… 
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