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peptidylglycine alpha-amidating monooxygenase

Known as: peptidylglycine monooxygenase, peptidylglycine hydroxylase, peptidylglycine alpha-hydroxylating monooxygenase 
National Institutes of Health

Related topics

Related topics

6 relations
MYCBP2 genePAM gene

Broader (2)

Mixed Function OxygenasesMultienzyme Complexes

Narrower (2)

alpha-amidation monooxygenasesubstance P-Gly12 protein, human

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2015
2015
Histidine-methionine contributions to function in copper proteins
Cuproproteins such as PHM and DBM mature in late endosmal vesicles of the mammalian secretory pathway where changes in vesicle pH… 
2013
2013
HHM motif at the CuH-site of peptidylglycine monooxygenase is a pH-dependent conformational switch.
Peptidylglycine monooxygenase is a copper-containing enzyme that catalyzes the amidation of neuropeptides hormones, the first… 
2011
2011
A copper-methionine interaction controls the pH-dependent activation of peptidylglycine monooxygenase.
The pH dependence of native peptidylglycine monooxygenase (PHM) and its M314H variant has been studied in detail. For wild-type… 
2006
2006
A pilot evaluation of the use of tissue microarrays for quantitation of target distribution in drug discovery pathology.
2006
2006
pH Dependence of peptidylglycine monooxygenase. Mechanistic implications of Cu-methionine binding dynamics.
The pH dependence of the PHM-catalyzed monooxygenation of dansyl-YVG was studied in two different buffer systems in the pH range… 
2004
2004
Kainic acid seizures in the rat: differential expression of chromogranin A, carboxypeptidase H and peptidylglycine α-amidating monooxigenase in subfields of the hippocampal formation
Using in situ hybridization histochemistry concentrations of mRNAs encoding chromogranin A (ChA), carboxypeptidase H (CPH) and… 
2001
2001
Characterization of a half-apo derivative of peptidylglycine monooxygenase. Insight into the reactivity of each active site copper.
A derivative of peptidylglycine monooxygenase which lacks the CuH center has been prepared and characterized. This form of the… 
2001
2001
Spectroscopic studies of peptidylglycine -hydroxylating monooxygenase: toward a mechanism of superoxide channeling
Spectroscopic Studies of Peptidylglycine a-Hydroxylating Monooxygenase. Toward a Mechanism of Superoxide Channeling Shulamit… 
Highly Cited
1999
Highly Cited
1999
Does superoxide channel between the copper centers in peptidylglycine monooxygenase? A new mechanism based on carbon monoxide reactivity.
Peptidylglycine monooxygenase (PHM) carries out the hydroxylation of the alpha-C atom of glycine-extended propeptides, the first… 
1994
1994
Purification and cDNA cloning of the two equine enzymes essential for the peptidyl-α-amidating reaction, peptidylglycine monooxygenase and peptidylamidoglycolate lyase
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