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peptidyl-lysine 5-dioxygenase activity

Known as: peptidyl-lysine, 2-oxoglutarate: oxygen oxidoreductase activity, lysine,2-oxoglutarate 5-dioxygenase activity, lysyl hydroxylase activity 
Catalysis of the reaction: protein L-lysine + 2-oxoglutarate + O2 = protein 5-hydroxy-L-lysine + succinate + CO2. [PMID:19574390]
National Institutes of Health

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1985
1985
In the absence of ascorbic acid, confluent human skin fibroblasts incubated in 0.5% serum-supplemented medium had one-third of…