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peptide deformylase activity

Known as: PDF activity, formyl-L-methionyl peptide amidohydrolase activity, polypeptide deformylase activity 
Catalysis of the reaction: formyl-L-methionyl peptide + H2O = formate + methionyl peptide. [EC:3.5.1.88, GOC:jl]
National Institutes of Health

Papers overview

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2018
2018
Unexpected peptide deformylase (PDF) genes were recently retrieved in numerous marine phage genomes. While various hypotheses… Expand
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2013
2013
Helicobacter pylori (H. pylori) is a major causative factor for gastrointestinal illnesses, H. pylori peptide deformylase (HpPDF… Expand
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2010
2010
The emergence of multi-drug-resistant strains of Staphylococcus epidermidis emphasizes the need to develop new antibiotics. The… Expand
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2004
2004
Deformylation of the initiator N-formylmethionine does not always proceed to completion for proteins overexpressed in Escherichia… Expand
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2003
2003
Recently we investigated the influence of classical and emerging antibiotics on the proteome of Bacillus subtilis including in… Expand
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2002
2002
La presente invention concerne le N-[1-oxo-2-alkyl-3-(N-hydroxyformamido)-propyl]-(carbonylamino-aryl ou heteroaryl)-azacyclo 4-7… Expand
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Highly Cited
1998
Highly Cited
1998
Previous work indicated that peptide deformylase behaves as a metalloenzyme since the Escherichia coli enzyme was shown to… Expand
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Highly Cited
1993
Highly Cited
1993
Overexpression of the fms gene, the first translation unit of a dicistronic operon that also encodes methionyl-tRNA(fMet… Expand
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