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peptide deformylase activity
Known as:
PDF activity
, formyl-L-methionyl peptide amidohydrolase activity
, polypeptide deformylase activity
Catalysis of the reaction: formyl-L-methionyl peptide + H2O = formate + methionyl peptide. [EC:3.5.1.88, GOC:jl]
National Institutes of Health
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Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2018
2018
Peptide deformylases from Vibrio parahaemolyticus phage and bacteria display similar deformylase activity and inhibitor binding clefts.
R. Grzela
,
Julien Nusbaum
,
+8 authors
C. Giglione
Biochimica et biophysica acta. Proteins and…
2018
Corpus ID: 4918179
2013
2013
Caffeic acid phenethyl ester (CAPE), an active component of propolis, inhibits Helicobacter pylori peptide deformylase activity.
K. Cui
,
Weiqiang Lu
,
Lili Zhu
,
Xu Shen
,
Jin Huang
Biochemical and biophysical research…
2013
Corpus ID: 26207130
2010
2010
Characterization of peptide deformylase homologues from Staphylococcus epidermidis.
Penghui Lin
,
T. Hu
,
+9 authors
D. Qu
Microbiology
2010
Corpus ID: 20734048
The emergence of multi-drug-resistant strains of Staphylococcus epidermidis emphasizes the need to develop new antibiotics. The…
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2004
2004
Increased peptide deformylase activity for N-formylmethionine processing of proteins overexpressed in Escherichia coli: application to homogeneous rubredoxin production.
Jianzhong Tang
,
G. Hernández
,
D. LeMaster
Protein expression and purification
2004
Corpus ID: 22867074
2003
2003
The role of peptide deformylase in protein biosynthesis: A proteomic study
J. Bandow
,
D. Becher
,
+4 authors
M. Hecker
Proteomics
2003
Corpus ID: 22237816
Recently we investigated the influence of classical and emerging antibiotics on the proteome of Bacillus subtilis including in…
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2002
2002
Composes de n-formyle hydroxylamine en tant qu'inhibiteurs de peptidyle deformylase (pdf)
D. V. Patel
,
Zhengyu Yuan
,
Rakesh K. Jain
,
S. Álvarez
,
Jeffrey W. Jacobs
2002
Corpus ID: 146030114
La presente invention concerne le N-[1-oxo-2-alkyl-3-(N-hydroxyformamido)-propyl]-(carbonylamino-aryl ou heteroaryl)-azacyclo 4-7…
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Highly Cited
1998
Highly Cited
1998
Control of peptide deformylase activity by metal cations.
S. Ragusa
,
S. Blanquet
,
T. Meinnel
Journal of molecular biology
1998
Corpus ID: 31865020
Previous work indicated that peptide deformylase behaves as a metalloenzyme since the Escherichia coli enzyme was shown to…
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Highly Cited
1993
Highly Cited
1993
Evidence that peptide deformylase and methionyl-tRNA(fMet) formyltransferase are encoded within the same operon in Escherichia coli
T. Meinnel
,
S. Blanquet
Journal of bacteriology
1993
Corpus ID: 24568337
Overexpression of the fms gene, the first translation unit of a dicistronic operon that also encodes methionyl-tRNA(fMet…
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