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peptide chemical synthesis

Known as: protein chemical synthesis 
National Institutes of Health

Related topics

Related topics

5 relations
BiotechnologyCombinatorial chemistryProtein Biosynthesissynthetic protein

Broader (1)

chemical synthesis

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2018
Highly Cited
2018
Serine/Threonine Ligation: Origin, Mechanistic Aspects, and Applications.
Synthetic proteins are expected to go beyond the boundary of recombinant DNA expression systems by being flexibly installed with… 
Highly Cited
2017
Highly Cited
2017
P-B Desulfurization: An Enabling Method for Protein Chemical Synthesis and Site-Specific Deuteration.
Cysteine-mediated native chemical ligation is a powerful method for protein chemical synthesis. Herein, we report an… 
Review
2017
Review
2017
A statistical view of protein chemical synthesis using NCL and extended methodologies.
Review
2016
Review
2016
Chemical synthesis of proteins using hydrazide intermediates
Protein chemical synthesis offers useful and otherwise-difficulty-to-obtain biomacromolecules for biological and pharmaceutical… 
Highly Cited
2015
Highly Cited
2015
Peptide o-aminoanilides as crypto-thioesters for protein chemical synthesis.
Fully unprotected peptide o-aminoanilides can be efficiently activated by NaNO2 in aqueous solution to furnish peptide thioesters… 
Highly Cited
2015
Highly Cited
2015
An efficient one-pot four-segment condensation method for protein chemical synthesis.
Successive peptide ligation using a one-pot method can improve the efficiency of protein chemical synthesis. Although one-pot… 
Highly Cited
2013
Highly Cited
2013
Development of new thioester equivalents for protein chemical synthesis.
The chemical synthesis of proteins provides synthetic chemists with an interesting challenge and supports biological research… 
Highly Cited
2012
Highly Cited
2012
A one-pot three-segment ligation strategy for protein chemical synthesis.
Protein chemical synthesis by native peptide ligation of unprotected peptide segments is an interesting complement and potential… 
Review
2010
Review
2010
The early years of retroviral protease crystal structures.
Soon after its discovery, the attempts to develop anti-AIDS therapeutics focused on the retroviral protease (PR)-an enzyme used… 
Review
2000
Review
2000
Challenges for protein chemical synthesis in the 21st century: bridging genomics and proteomics.
The Human Genome Project and other major sequencing projects have rapidly provided a vast array of new protein sequences. In the… 
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