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pegylated interferon alfa

Known as: PEG-IFN-a, PEG-IFNA, PEG-interferon alfa 
A covalent conjugate of recombinant interferon alpha and polyethylene glycol (PEG), used as an antiviral and antineoplastic agent. The biological… Expand
National Institutes of Health

Papers overview

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Review
2018
Review
2018
Viruses are the smallest known microbes, yet they cause the most significant losses in human health. Most of the time, the best… Expand
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Highly Cited
2016
Highly Cited
2016
BACKGROUND Treatment of patients with chronic hepatitis B (CHB) with nucleos(t)ide analogues (NAs) suppresses hepatitis B virus… Expand
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Highly Cited
2016
Highly Cited
2016
Hepatitis C virus (HCV)–infected patients with cirrhosis are historically a difficult‐to‐treat population and are at risk of… Expand
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Highly Cited
2014
Highly Cited
2014
BACKGROUND Although the addition of the HCV NS3/4A protease inhibitors boceprevir and telaprevir to pegylated interferon… Expand
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Highly Cited
2014
Highly Cited
2014
BACKGROUND Pegylated interferon (peginterferon) alfa 2a or 2b plus ribavirin regimens were the standard of care in patients with… Expand
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Highly Cited
2010
Highly Cited
2010
BACKGROUND & AIMS Hepatitis C virus (HCV) induces chronic infection in 50% to 80% of infected persons; approximately 50% of these… Expand
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Highly Cited
2009
Highly Cited
2009
Since the introduction of the hepatitis B vaccine and other preventive measures, the worldwide prevalence of hepatitis B… Expand
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Highly Cited
2008
Highly Cited
2008
A recent nonrandomized pilot trial showed that hepatitis C virus (HCV) patients with genotype 2/3 and rapid virological response… Expand
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Highly Cited
2006
Highly Cited
2006
BACKGROUND & AIMS Pegylated interferon alfa-ribavirin combination is the standard treatment for chronic hepatitis C, but the… Expand
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Highly Cited
2005
Highly Cited
2005
BACKGROUND Current treatments for chronic hepatitis B are suboptimal. In the search for improved therapies, we compared the… Expand
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