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peginterferon alfa-2a

Known as: PEG-interferon alfa-2A, PEG-IFN alpha-2a, peginterferon alfa-2a [Chemical/Ingredient] 
A covalent conjugate of recombinant interferon alfa, subtype 2a, and polyethylene glycol (PEG), used as an antiviral and antineoplastic agent. The… Expand
National Institutes of Health

Papers overview

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Highly Cited
2009
Highly Cited
2009
BACKGROUND Treatment guidelines recommend the use of peginterferon alfa-2b or peginterferon alfa-2a in combination with ribavirin… Expand
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Highly Cited
2009
Highly Cited
2009
BACKGROUND In patients with chronic infection with hepatitis C virus (HCV) genotype 1, treatment with peginterferon alfa and… Expand
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Highly Cited
2007
Highly Cited
2007
BACKGROUND Patients infected with hepatitis C virus (HCV) genotype 2 or 3 have sustained virologic response rates of… Expand
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Highly Cited
2005
Highly Cited
2005
BACKGROUND Current treatments for chronic hepatitis B are suboptimal. In the search for improved therapies, we compared the… Expand
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Highly Cited
2004
Highly Cited
2004
BACKGROUND Available treatments for hepatitis B e antigen (HBeAg)-negative chronic hepatitis B are associated with poor sustained… Expand
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Highly Cited
2004
Highly Cited
2004
BACKGROUND Chronic hepatitis C virus (HCV) infection is a cause of major complications in persons who are also infected with the… Expand
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Highly Cited
2004
Highly Cited
2004
BACKGROUND Hepatitis C virus (HCV) infection is highly prevalent and is associated with substantial morbidity and mortality among… Expand
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Highly Cited
2002
Highly Cited
2002
BACKGROUND Treatment with peginterferon alfa-2a alone produces significantly higher sustained virologic responses than treatment… Expand
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Highly Cited
2000
Highly Cited
2000
BACKGROUND Covalent attachment of a 40-kd branched-chain polyethylene glycol moiety to interferon alfa-2a results in a compound… Expand
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Highly Cited
2000
Highly Cited
2000
BACKGROUND Chronic hepatitis C virus (HCV) infection in patients with cirrhosis is difficult to treat. In patients with chronic… Expand
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