peginterferon alfa-2a

Known as: PEG-interferon alfa-2a, PEG-IFN alpha-2A, peginterferon alfa-2a [Chemical/Ingredient] 
A covalent conjugate of recombinant interferon alfa, subtype 2a, and polyethylene glycol (PEG), used as an antiviral and antineoplastic agent. The… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1981-2017
05019812017

Papers overview

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Highly Cited
2010
Highly Cited
2010
BACKGROUND Imatinib (400 mg daily) is considered the best initial therapy for patients with newly diagnosed chronic myeloid… (More)
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Highly Cited
2009
Highly Cited
2009
BACKGROUND Treatment guidelines recommend the use of peginterferon alfa-2b or peginterferon alfa-2a in combination with ribavirin… (More)
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Highly Cited
2009
Highly Cited
2009
BACKGROUND Current therapy for chronic hepatitis C virus (HCV) infection is effective in less than 50% of patients infected with… (More)
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Highly Cited
2005
Highly Cited
2005
BACKGROUND Current treatments for chronic hepatitis B are suboptimal. In the search for improved therapies, we compared the… (More)
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Highly Cited
2005
Highly Cited
2005
BACKGROUND Patients infected with hepatitis C virus (HCV) genotype 2 or 3 have sustained virologic response rates of… (More)
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Highly Cited
2005
Highly Cited
2005
BACKGROUND/AIMS Prediction of sustained virological response (SVR) during treatment would allow clinicians to identify patients… (More)
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Highly Cited
2004
Highly Cited
2004
BACKGROUND Available treatments for hepatitis B e antigen (HBeAg)-negative chronic hepatitis B are associated with poor sustained… (More)
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Highly Cited
2004
Highly Cited
2004
BACKGROUND Chronic hepatitis C virus (HCV) infection is a cause of major complications in persons who are also infected with the… (More)
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Highly Cited
2002
Highly Cited
2002
BACKGROUND Treatment with peginterferon alfa-2a alone produces significantly higher sustained virologic responses than treatment… (More)
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Highly Cited
2000
Highly Cited
2000
BACKGROUND Chronic hepatitis C virus (HCV) infection in patients with cirrhosis is difficult to treat. In patients with chronic… (More)
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