pegfilgrastim

Known as: SD-01-filgrastim, filgrastim-SD/01, SD-01 sustained duration G-CSF 
A long-acting pegylated form of a recombinant therapeutic agent which is chemically identical to or similar to an endogenous human granulocyte colony… (More)
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2011
Review
2011
Pegfilgrastim is a sustained-duration form of filgrastim, a recombinant methionyl form of human granulocyte colony-stimulating… (More)
Is this relevant?
Highly Cited
2008
Highly Cited
2008
BACKGROUND TAC (docetaxel/doxorubicin/cyclophosphamide) is associated with high incidences of grade 4 neutropenia and febrile… (More)
  • figure 1
  • table 1
  • table 2
  • figure 2
  • table 3
Is this relevant?
2006
2006
This analysis was conducted to characterize the pharmacokinetics and pharmacodynamics of pegfilgrastim and to develop a… (More)
Is this relevant?
Highly Cited
2005
Highly Cited
2005
PURPOSE We evaluated the efficacy of pegfilgrastim to reduce the incidence of febrile neutropenia associated with docetaxel in… (More)
Is this relevant?
Review
2004
Review
2004
Recombinant protein technology produces drugs for human therapy in unprecedented quantity and quality. Research is now focusing… (More)
Is this relevant?
Highly Cited
2003
Highly Cited
2003
BACKGROUND We evaluated the efficacy of a single fixed 6 mg dose of pegfilgrastim (a pegylated version of filgrastim) per cycle… (More)
  • table 1
  • table 2
  • table 3
  • table 4
  • figure 1
Is this relevant?
Highly Cited
2003
Highly Cited
2003
PURPOSE The primary objective was to assess the duration of grade 4 neutropenia (neutrophil count < 0.5 x 10(9)/L) after one… (More)
Is this relevant?
Review
2003
Review
2003
Pegfilgrastim is a granulocyte colony-stimulating factor (G-CSF) with a long half-life and sustained duration of action… (More)
Is this relevant?
Highly Cited
2002
Highly Cited
2002
PURPOSE This multicenter, randomized, double-blind, active-control study was designed to determine whether a single subcutaneous… (More)
Is this relevant?
Highly Cited
2002
Highly Cited
2002
BACKGROUND Neutropenia is common in patients receiving myelotoxic chemotherapy. Pegfilgrastim, a sustained-duration filgrastim is… (More)
  • table 1
  • table 2
  • table 3
  • figure 1
  • figure 2
Is this relevant?