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parecoxib

Known as: N-(((5-methyl-3-phenylisoxazol-4-yl)-phenyl)sulfonyl)propanamide, N-(((Me-P)-P)S)P, Propanamide, N-((4-(5-methyl-3-phenyl-4- isoxazolyl)phenyl)sulfonyl)- 
An amide prodrug of the cyclooxygenase II (COX-2) selective, non-steroidal anti-inflammatory drug (NSAID) valdecoxib, with anti-inflammatory… Expand
National Institutes of Health

Papers overview

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Highly Cited
2010
Highly Cited
2010
The enzyme cyclooxygenase-2 (COX-2), which catalyzes the production of pro-inflammatory prostaglandins, is induced in the brain… Expand
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Highly Cited
2006
Highly Cited
2006
In this prospective, double-blind, randomized, placebo-controlled study we compared the efficacy of three IV non-opioid… Expand
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Highly Cited
2006
Highly Cited
2006
Background: Valdecoxib and its intravenous prodrug parecoxib are reported to increase thromboembolic risk after coronary artery… Expand
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Review
2006
Review
2006
CONTEXT Adverse effects of selective cyclooxygenase 2 (COX-2) inhibitors on renal events and arrhythmia have been controversial… Expand
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Highly Cited
2005
Highly Cited
2005
BACKGROUND Valdecoxib and its intravenous prodrug parecoxib are used to treat postoperative pain but may involve risk after… Expand
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Highly Cited
2005
Highly Cited
2005
Approximately six years after the cyclooxygenase-2 (COX-2) inhibitors were approved for use in the United States, the results of… Expand
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Highly Cited
2005
Highly Cited
2005
Selective inhibitors of cyclooxygenase (COX)-21 depress prostacyclin (PGI2) but not COX-1–derived thromboxane A2. The effects of… Expand
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Highly Cited
2004
Highly Cited
2004
Background Cyclooxygenase-2 inhibitors inhibit bone repair. Hypothesis Cyclooxygenase inhibitors might also have a negative… Expand
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Highly Cited
2004
Highly Cited
2004
&NA; Non‐steroidal antiinflammatory drugs (NSAIDs) are known to induce analgesia mainly via inhibition of cyclooxygenase (COX… Expand
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Highly Cited
2003
Highly Cited
2003
OBJECTIVE Inhibition of cyclooxygenase 2 provides analgesia in ambulatory patients. We prospectively evaluated the safety and… Expand
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