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parbendazole

Known as: Methyl 5-butyl-2-benzimidazolecarbamate, 5-Butyl-2-(carbomethoxyamino)benzimidazole, Parbendazol 
National Institutes of Health

Related topics

Related topics

3 relations

Broader (2)

Antinematodal AgentsBenzimidazoles

Narrower (1)

helmatac

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2019
2019
The Benzimidazole-Based Anthelmintic Parbendazole: A Repurposed Drug Candidate That Synergizes with Gemcitabine in Pancreatic Cancer
Pancreatic cancer (PC) is one of the most lethal, chemoresistant malignancies and it is of paramount importance to find more… Expand
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Highly Cited
2015
Highly Cited
2015
Connectivity Map-based discovery of parbendazole reveals targetable human osteogenic pathway
Significance Osteoporosis, a disease characterized by increased bone fragility and fracture risk, affects over 20% of the ever… Expand
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1998
1998
Oral pharmacological treatments for parasitic diseases of rainbow trout Oncorhynchus mykiss. I: Hexamita salmonis.
Various drugs were evaluated as regards efficacy for the treatment of Hexamita salmonis infection in rainbow trout. The results… Expand
Highly Cited
1996
Highly Cited
1996
Albendazole resistance in Giardia is correlated with cytoskeletal changes but not with a mutation at amino acid 200 in beta-tubulin.
Albendazole resistance was induced in three different Giardia cultures following growth in successively increasing amounts of… Expand
Highly Cited
1986
Highly Cited
1986
Interactions of benzimidazoles (BZ) with tubulin from BZ-sensitive and BZ-resistant isolates of Haemonchus contortus.
The binding of tritiated benzimidazoles (BZs)-albendazole, parbendazole, oxibendazole, mebendazole, oxfendazole and fenbendazole… Expand
Highly Cited
1985
Highly Cited
1985
Potentiation of the anthelmintic activity of oxfendazole by parbendazole.
The ability of parbendazole (PBZ) to potentiate co-administered oxfendazole (OFZ) was investigated. Administration of a range (1… Expand
1981
1981
A correlation between in vivo and in vitro effects of the microtubule inhibitors colchicine, parbendazole and nocodazole on myxamoebae of Physarum polycephalum.
The effects of the microtubule inhibitors colchicine, parbendazole and nocodazole on the growth of myxamoebae of Physarum… Expand
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1981
1981
Binding of parbendazole to tubulin and its influence on microtubules in tissue-culture cells as revealed by immunofluorescence microscopy.
We have shown that the benzimidazole carbamate, parbendazole, is a potent inhibitor of microtubule assembly in vitro and in vivo… Expand
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Highly Cited
1978
Highly Cited
1978
Interaction of anthelmintic benzimidazoles and benzimidazole derivatives with bovine brain tubulin.
The binding and inhibitory properties of 11 benzimidazoles for bovine brain tubulin were investigated. The effects of the… Expand
1977
1977
The effect of route of administration on the anthelmintic efficacy of benzimidazole anthelmintics in sheep infected with strains of Haemonchus contortus and Trichostrongylus colubriformis resistant…
Observations of erratic anthelmintic activity of fenbendazole against known standardised thiabendazole-resistant strains of… Expand
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