pantoprazole

Known as: Pantoprazolum, 1H-Benzimidazole, 5-(difluoromethoxy)-2-(((3,4-dimethoxy-2-pyridinyl)methyl)sulfinyl)-, pantoprazole [Chemical/Ingredient] 
A substituted benzimidazole and proton pump inhibitor with antacid activity. Pantoprazole is a lipophilic weak base that crosses the parietal cell… (More)
National Institutes of Health

Papers overview

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Highly Cited
2011
Highly Cited
2011
Four randomized, placebo-controlled, crossover studies were conducted among 282 healthy subjects to investigate whether an… (More)
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Highly Cited
2009
Highly Cited
2009
BACKGROUND Clopidogrel is activated by CYP2C19, which also metabolizes proton pump inhibitors (PPI). As proton pump inhibitors… (More)
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Highly Cited
2009
Highly Cited
2009
OBJECTIVES This study sought to compare the effect of 2 proton pump inhibitors (PPIs) on platelet response to clopidogrel after… (More)
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Highly Cited
2009
Highly Cited
2009
BACKGROUND Most proton pump inhibitors inhibit the bioactivation of clopidogrel to its active metabolite. The clinical… (More)
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Highly Cited
2005
Highly Cited
2005
Imatinib mesylate (signal transduction inhibitor 571, Gleevec) is a potent and selective tyrosine kinase inhibitor, which was… (More)
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Highly Cited
2004
Highly Cited
2004
The human clearance of proton pump inhibitors (PPIs) of the substituted benzimidazole class is conducted primarily by the hepatic… (More)
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Highly Cited
2003
Highly Cited
2003
OBJECTIVES:Proton pump inhibitors owe their clinical efficacy to their ability to suppress gastric acid production. The objective… (More)
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Review
2002
Review
2002
Cytochrome P450 2C19 (CYP2C19) is the main (or partial) cause for large differences in the pharmacokinetics of a number of… (More)
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Highly Cited
2001
Highly Cited
2001
Proton pump inhibitors are a class of drugs which are widely prescribed for acid-related diseases. They are primarily metabolized… (More)
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Review
1996
Review
1996
The proton pump inhibitor pantoprazole is a substituted benzimidazole sulphoxide for the treatment of acid-related… (More)
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