Semantic Scholar uses AI to extract papers important to this topic.
Four randomized, placebo‐controlled, crossover studies were conducted among 282 healthy subjects to investigate whether an… Expand BACKGROUND
Clopidogrel is activated by CYP2C19, which also metabolizes proton pump inhibitors (PPI). As proton pump inhibitors… Expand Background: Most proton pump inhibitors inhibit the bioactivation of clopidogrel to its active metabolite. The clinical… Expand Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) are rare but severe cutaneous adverse reactions (SCAR… Expand Elective esophageal variceal ligation (EVL) is performed to decrease the risk of variceal hemorrhage. Side effects of EVL include… Expand The human clearance of proton pump inhibitors (PPIs) of the substituted benzimidazole class is conducted primarily by the hepatic… Expand OBJECTIVES:Proton pump inhibitors owe their clinical efficacy to their ability to suppress gastric acid production. The objective… Expand Cytochrome P450 2C19 (CYP2C19) is the main (or partial) cause for large differences in the pharmacokinetics of a number of… Expand Abstract. Proton pump inhibitors are a class of drugs which are widely prescribed for acid-related diseases. They are primarily… Expand Proton pump inhibitors have dramatically influenced the management of acid‐peptic disorders in recent years. They all have a… Expand