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pantoprazole

Known as: Pantoprazolum, 1H-Benzimidazole, 5-(difluoromethoxy)-2-(((3,4-dimethoxy-2-pyridinyl)methyl)sulfinyl)-, pantoprazole [Chemical/Ingredient] 
A substituted benzimidazole and proton pump inhibitor with antacid activity. Pantoprazole is a lipophilic weak base that crosses the parietal cell… Expand
National Institutes of Health

Papers overview

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Highly Cited
2011
Highly Cited
2011
Four randomized, placebo‐controlled, crossover studies were conducted among 282 healthy subjects to investigate whether an… Expand
Highly Cited
2009
Highly Cited
2009
BACKGROUND Clopidogrel is activated by CYP2C19, which also metabolizes proton pump inhibitors (PPI). As proton pump inhibitors… Expand
Highly Cited
2009
Highly Cited
2009
Background: Most proton pump inhibitors inhibit the bioactivation of clopidogrel to its active metabolite. The clinical… Expand
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Highly Cited
2008
Highly Cited
2008
Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) are rare but severe cutaneous adverse reactions (SCAR… Expand
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Highly Cited
2005
Highly Cited
2005
Elective esophageal variceal ligation (EVL) is performed to decrease the risk of variceal hemorrhage. Side effects of EVL include… Expand
Highly Cited
2004
Highly Cited
2004
The human clearance of proton pump inhibitors (PPIs) of the substituted benzimidazole class is conducted primarily by the hepatic… Expand
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Highly Cited
2003
Highly Cited
2003
OBJECTIVES:Proton pump inhibitors owe their clinical efficacy to their ability to suppress gastric acid production. The objective… Expand
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Review
2002
Review
2002
Cytochrome P450 2C19 (CYP2C19) is the main (or partial) cause for large differences in the pharmacokinetics of a number of… Expand
Highly Cited
2001
Highly Cited
2001
Abstract. Proton pump inhibitors are a class of drugs which are widely prescribed for acid-related diseases. They are primarily… Expand
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Review
2000
Review
2000
Proton pump inhibitors have dramatically influenced the management of acid‐peptic disorders in recent years. They all have a… Expand