pancreas development

The process whose specific outcome is the progression of the pancreas over time, from its formation to the mature structure. The pancreas is an… (More)
National Institutes of Health

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Highly Cited
2007
Highly Cited
2007
The liver and pancreas are specified from the foregut endoderm through an interaction with the adjacent mesoderm. However, the… (More)
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Highly Cited
2006
Highly Cited
2006
SMAD4 is inactivated in the majority of pancreatic ductal adenocarcinomas (PDAC) with concurrent mutational inactivation of the… (More)
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Review
2006
Review
2006
The development of insulin-producing pancreatic beta (beta)-cells represents the culmination of a complex developmental program… (More)
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Highly Cited
2004
Highly Cited
2004
The pancreatic islet is necessary for maintaining glucose homeostasis. Within the pancreatic islet, the homeodomain protein Nkx2… (More)
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Highly Cited
2003
Highly Cited
2003
DNA microarray analysis was combined with a modified single-cell PCR procedure to study gene expression profiles of single cells… (More)
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Highly Cited
2000
Highly Cited
2000
Pancreas organogenesis is regulated by the interaction of distinct signaling pathways that promote or restrict morphogenesis and… (More)
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Highly Cited
2000
Highly Cited
2000
Diabetes is caused by a failure of the pancreas to produce insulin in amounts sufficient to meet the body's needs. A hallmark of… (More)
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Highly Cited
1998
Highly Cited
1998
Notochord signals to the endoderm are required for development of the chick dorsal pancreas. Sonic hedgehog (SHH) is normally… (More)
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Highly Cited
1997
Highly Cited
1997
The role of the notochord in inducing and patterning adjacent neural and mesodermal tissues is well established. We provide… (More)
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Highly Cited
1994
Highly Cited
1994
THE mammalian pancreas is a mixed exocrine and endocrine gland that, in most species, arises from ventral and dorsal buds which… (More)
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