Skip to search formSkip to main content
You are currently offline. Some features of the site may not work correctly.

pagoclone

Known as: 1H-Isoindol-1-One, 2-(7-Chloro-1,8-Naphthyridin-2-yl)-2,3-Dihydro-3-(5-Methyl-2-Oxohexyl)-, (+)-, 2-(7-chloro-1.8-naphthyridin-2-yl)-2,3-dihydro-3-(5-methyl-2-oxohexyl)-1H-isoindol-1-one 
 
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2019
2019
A practical one-pot isoindolinone synthesis enabled by RhIII catalysis was developed. The advantage of this protocol is that it… Expand
Is this relevant?
2011
2011
La presente invention concerne une composition pharmaceutique pour le traitement, le soulagement ou la prevention de maladies… Expand
Is this relevant?
2010
2010
INTRODUCTION Stuttering is a speech disorder in which the flow of speech is disrupted by repetitions, prolongation, and blocks of… Expand
Is this relevant?
2008
2008
In this study a novel series of isoindol-1-one and isoindol-1,3-dione derivatives for beta-amyloid-specific binding agents is… Expand
Is this relevant?
2008
2008
Pagoclone is a novel cyclopyrrolone that acts as a partial GABAA receptor agonist. Preclinical studies suggest that pagoclone may… Expand
  • table 1
  • table 2
Is this relevant?
2006
2006
The cyclopyrrolone pagoclone binds with roughly equivalent high affinity (0.7-9.1nM) to the benzodiazepine binding site of human… Expand
  • figure 1
  • table 1
  • figure 2
  • table 2
  • figure 3
Is this relevant?
2006
2006
This study assessed the abuse potential of pagoclone, a partial agonist at the gamma-aminobutyric acid type A (GABAA… Expand
Is this relevant?
2005
2005
The GABA-ergic system is central to many anxiety disorders and has therefore received much attention. Benzodiazepines are highly… Expand
  • figure 1
Is this relevant?
Review
2003
Review
2003
  • Alan N. Bateson
  • Current opinion in investigational drugs
  • 2003
  • Corpus ID: 34466303
Pagoclone is a cyclopyrrolone GABAA receptor modulator under development by Indevus for the potential treatment of panic and… Expand
Is this relevant?
2001
2001
Pagoclone is a cyclopyrrolone that is believed to act as a partial agonist at the γ-aminobutyric acid (GABA) A/benzodiazepine… Expand
  • figure 1
  • table 1
  • table 2
  • figure 2
Is this relevant?