p80(NPM-ALK) protein

Known as: NPM1-ALK Fusion Protein, protein tyrosine kinase p80(NPM-ALK), NPM1/ALK Fusion Protein 
A fusion protein (680 aa, ~75 kDa) that is encoded by the NPM1/ALK fusion gene. This protein contains the N-terminal domain from the nucleophosmin… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1967-2017
0102019672017

Papers overview

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2012
2012
Anaplastic large cell lymphoma (ALCL) is an aggressive non-Hodgkin's lymphoma found in children and young adults. ALCLs… (More)
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Highly Cited
2011
Highly Cited
2011
Anaplastic lymphoma kinase (ALK) is a tyrosine kinase that is constitutively activated in certain cancers, following gene… (More)
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2011
Highly Cited
2011
Many transformed lymphoma cells show immune-phenotypes resembling the corresponding normal lymphocytes; thus, they provide a… (More)
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2011
2011
The anaplastic lymphoma kinase (ALK), tyrosine kinase oncogene is implicated in a wide variety of cancers. In this study we used… (More)
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Highly Cited
2008
Highly Cited
2008
Anaplastic large cell lymphoma (ALCL) is a T/null-cell neoplasm characterized by chromosomal translocations involving the… (More)
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2007
2007
Anaplastic large-cell lymphoma (ALCL) frequently carries the t(2;5)(p23;q35), resulting in aberrant expression of nucleophosmin… (More)
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Highly Cited
2002
Highly Cited
2002
ALK-positive anaplastic large-cell lymphoma (ALCL) has been recognized as a distinct type of lymphoma in the heterogeneous group… (More)
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2001
2001
Anaplastic large cell lymphoma (ALCL) is frequently associated with the t(2;5)(p23;q35) translocation. It creates a NPM-ALK… (More)
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Highly Cited
2000
Highly Cited
2000
The subset of CD30-positive anaplastic large cell lymphomas (ALCL) with the NPM-ALK gene fusion arising from the t(2;5)(p23;q35… (More)
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Highly Cited
1998
Highly Cited
1998
Large-cell anaplastic lymphoma is a subtype of non-Hodgkin's lymphoma characterized by the expression of CD30. More than half of… (More)
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