Skip to search formSkip to main contentSkip to account menu

p80(NPM-ALK) protein

Known as: NPM1-ALK Fusion Protein, protein tyrosine kinase p80(NPM-ALK), NPM-ALK Fusion Protein 
A fusion protein (680 aa, ~75 kDa) that is encoded by the NPM1/ALK fusion gene. This protein contains the N-terminal domain from the nucleophosmin… 
National Institutes of Health

Related topics

Related topics

4 relations
Fusion GeneNPM1 geneTyrosine Phosphorylation

Broader (1)

Protein Tyrosine Kinase

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2011
2011
NPM-ALK and the JunB transcription factor regulate the expression of cytotoxic molecules in ALK-positive, anaplastic large cell lymphoma.
Anaplastic lymphoma kinase-positive, anaplastic large cell lymphoma (ALK+ ALCL) is an aggressive non-Hodgkin lymphoma of T/null… 
Highly Cited
2009
Highly Cited
2009
IGF-IR tyrosine kinase interacts with NPM-ALK oncogene to induce survival of T-cell ALK+ anaplastic large-cell lymphoma cells.
Type I insulin-like growth factor receptor (IGF-IR) tyrosine kinase plays important roles in the pathogenesis of several… 
2009
2009
Kinetics of humoral response to ALK and its relationship with minimal residual disease in pediatric ALCL
Kinetics of humoral response to ALK and its relationship with minimal residual disease in pediatric ALCL 
Highly Cited
2005
Highly Cited
2005
p130Cas mediates the transforming properties of the anaplastic lymphoma kinase.
Translocations of the anaplastic lymphoma kinase (ALK) gene have been described in anaplastic large-cell lymphomas (ALCLs) and in… 
2005
2005
Mice transgenic for NPM-ALK develop non-Hodgkin lymphomas.
BACKGROUND The t(2;5)(p23;q35) translocation is associated with a high percentage of anaplastic large-cell lymphomas (ALCL) of T… 
Highly Cited
2003
Highly Cited
2003
Nucleophosmin-anaplastic lymphoma kinase of anaplastic large-cell lymphoma recruits, activates, and uses pp60c-src to mediate its mitogenicity.
Anaplastic large-cell lymphomas (ALCLs) are lymphomas of T or null phenotype often associated with a chromosomal translocation, t… 
2002
2002
Model of inhibition of the NPM-ALK kinase activity by herbimycin A.
Anaplastic large cell lymphoma (ALCL) exhibiting the t(2;5) translocation is characterized by the resulting expression of the… 
Highly Cited
1995
Highly Cited
1995
RFLP mapping of quantitative trait loci controlling seed aliphatic-glucosinolate content in oilseed rape (Brassica napus L)
We report the RFLP mapping of quantitative trait loci (QTLs) which regulate the total seed aliphaticglucosinolate content in… 
Highly Cited
1983
Highly Cited
1983
Quantitative analysis of ether-linked lipids as alkyl- and alk-1-enyl-glycerol benzoates by high-performance liquid chromatography.
Highly Cited
1977
Highly Cited
1977
Characterization of the alkyl ether species of phosphatidylcholine in bovine heart.
The molecular types of lecithin in beef heart lipids were investigated by a combination of mild hydrolytic procedures and silicic… 
By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy Policy (opens in a new tab), Terms of Service (opens in a new tab), and Dataset License (opens in a new tab)