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p110beta/delta PI3K Inhibitor GS-9820

Known as: GS-9820 
An inhibitor of the beta and delta isoforms of the 110 kDa catalytic subunit of class IA phosphoinositide-3 kinases (PI3K) with potential… Expand
National Institutes of Health

Papers overview

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2018
2018
Final results of a phase 1b study of the safety and efficacy of the PI3Kδ inhibitor acalisib (GS-9820) in relapsed/refractory… Expand
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2016
2016
Partial inhibition of PI3K is one of the best-validated and evolutionary conserved manipulations to extend longevity. The best… Expand
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2016
2016
Introduction: Phosphatidylinositol-3-kinase δ (PI3Kδ)-signaling provides key maintenance, proliferation, and survival cues during… Expand
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Review
2015
Review
2015
The healthy immune system protects against infection and malignant transformation without causing significant damage to host… Expand
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2013
2013
Background: Little is known about the function of specific phosphatidylinositol 3-kinase (PI3K) isoforms in osteoclasts. Results… Expand
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2013
2013
Background In B-cells, phosphatidylinositol 3-kinase delta (PI3Kd) mediates a positive effect on cell survival, proliferation… Expand
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2013
2013
Juvenile myelomonocytic leukemia (JMML) is a fatal leukemia affecting children under the age of 4 years and is characterized by… Expand
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2012
2012
Abstract 4017 Phosphatidylinositide 3-kinases (PI3K) are a family of lipid kinases that are involved in signaling events which… Expand
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