p-cyanophenylalanine
National Institutes of Health
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The use of selenomethionine (MSe)-p-cyanophenylalanine (FCN) pairs to probe protein structure is demonstrated. MSe quenches FCN…
The C≡N stretching frequency and fluorescence quantum yield of p-cyanophenylalanine are sensitive to environment. As such, this…
The magnitude of the membrane dipole field was measured using vibrational Stark effect (VSE) shifts of nitrile oscillators placed…
The human cathelicidin peptide LL-37 is an important effector of our innate immune system and contributes to host defence with…
We have recently shown that p-cyanophenylalanine (Cnf) and a thioamide can be used as a minimally perturbing Förster resonant…
Decreasing the size of spectroscopic probes can afford higher-resolution structural information from fluorescence experiments…
Three different nitrile-containing amino acids, p-cyanophenylalanine, m-cyanophenylalanine, and S-cyanohomocysteine, have been…
The use of noncoded amino acids as spectroscopic probes of protein folding and function is growing rapidly, in large part because…
Amyloid formation has been implicated in more than fifteen different human diseases including Alzheimer’s disease, Parkinson’s…