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oxidative deethylation

The process of removing one or more ethyl groups from a molecule, involving the oxidation (i.e. electron loss) of one or more atoms in the substrate… Expand
National Institutes of Health

Papers overview

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2010
2010
SummaryPhenacetinO-deethylation is a marker reaction of CYP450 1A2 activity. The drug-metabolizing enzyme is constitutively… Expand
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2002
2002
Cytochrome P450 CYP1A1 is expressed in most tissues. In brain and kidney, its function remains unclear because its enzymatic… Expand
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Highly Cited
2000
Highly Cited
2000
The UDP-glucuronosyltransferases (UGTs) are a superfamily of membrane-bound enzymes whose active site is localized inside the… Expand
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Highly Cited
1999
Highly Cited
1999
The ability of antipsychotic drugs to inhibit the catalytic activity of five cytochrome P-450 (CYP) isoforms was compared using… Expand
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1997
1997
Aryl acetylenes have been investigated as inhibitors of cytochrome P450 (P450)-dependent alkoxyresorufin dealkylation… Expand
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Highly Cited
1996
Highly Cited
1996
The stability of curcumin, as well as the interactions between curcumin and cytochrome P450s (P450s) and glutathione S… Expand
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1996
1996
Aiming the selection of possible candidates for the reactor cells in a hybrid artificial liver, we investigated the activities of… Expand
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1987
1987
Multiple doses of beta-naphthoflavone to iron-loaded C57BL/10ScSn mice for 6 weeks caused inhibition of hepatic uroporphyrinogen… Expand
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1979
1979
The influence of cobaltous chloride treatment on various functions of microsomal cytochromes was studied in C57BL6J Han mice. Two… Expand
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Highly Cited
1978
Highly Cited
1978
Deethylation of ethoxycoumarin as a measure of monooxygenase activity was introduced by Ullrich and Weber (Hoppe-Seyler’s Z… Expand
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