oxetanocin G

Known as: 6H-Purin-6-one, 2-amino-9-(3,4-bis(hydroxymethyl)-2-oxetanyl)-1,9-dihydro-, (2R-(2alpha,3beta,4alpha))-, OXT-G

National Institutes of Health

Papers overview

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2006

2006

Synthetic Nucleosides and Nucleotides. 43. Inhibition of Vertebrate Telomerases by Carbocyclic Oxetanocin G (C.OXT-G) Triphosphate Analogues and Influence of C.OXT-G Treatment on Telomere Length in…

Toyofumi YamaguchiM. Saneyoshi T. Maruyama
Nucleosides, Nucleotides & Nucleic Acids
2006
Corpus ID: 42728221

Telomerase, responsible for telomere synthesis, is expressed in ∼ 90% of human tumor cells but seldom in normal somatic cells. In…