orotate phosphoribosyltransferase activity

Known as: orotidine 5'-monophosphate pyrophosphorylase activity, orotidine-5'-phosphate:diphosphate phospho-alpha-D-ribosyl-transferase activity, OPRT activity 
Catalysis of the reaction: orotidine 5'-phosphate + diphosphate = orotate + 5-phospho-alpha-D-ribose 1-diphosphate. [EC:2.4.2.10]
National Institutes of Health

Topic mentions per year

Topic mentions per year

1959-2017
02419592017

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2009
2009
We have previously shown that orotate phosphoribosyltransferase (OPRT) and orotidine 5'-monophosphate decarboxylase (OMPDC) in… (More)
  • figure 1
  • table 3
  • table 1
  • table 2
  • figure 2
Is this relevant?
2008
2008
To elucidate the mechanism of resistance to 5-fluorouracil (5-FU) in human gastric cancer cells, we established a cell line MKN45… (More)
  • figure 1
  • table I
  • figure 2
  • figure 4
  • figure 5
Is this relevant?
2008
2008
ADP-glucose (Glc) pyrophosphorylase (ADP-Glc PPase) catalyzes the first committed step in starch biosynthesis. Higher plant ADP… (More)
  • figure 1
  • table I
  • figure 2
  • table II
  • figure 3
Is this relevant?
2007
2007
The genes encoding orotate phosphoribosyltransferase (OPRT) and orotidine-5'-monophosphate decarboxylase (OMPDC), the fifth and… (More)
Is this relevant?
2004
2004
BACKGROUND 5-Fluorouracil (5-FU), an antitumor agent, is used clinically against a variety of malignancies, including bladder… (More)
Is this relevant?
2004
2004
PURPOSE The anticancer agent 5-fluorouracil (5-FU) is clinically used against various cancers, including renal cell carcinoma… (More)
Is this relevant?
2004
2004
The allosteric enzyme ADP-Glc pyrophosphorylase (AGPase) catalyzes the synthesis of ADP-Glc, a rate-limiting step in starch… (More)
Is this relevant?
1999
1999
To investigate the role of the C-terminal region on the activity and thermostability of orotate phosphoribosyltransferase… (More)
Is this relevant?
1976
1976
An enzymatic assay for measurement of inorganic pyrophosphate (PPi) in biological samples is described using the UDPG… (More)
Is this relevant?
1968
1968
GENETIC variants of several mammalian cell lines which are not able to incorporate preformed purine or nucleoside into the cell's… (More)
Is this relevant?