FAQ

orotate phosphoribosyltransferase activity

Known as: orotidine 5'-monophosphate pyrophosphorylase activity, orotidine-5'-phosphate:diphosphate phospho-alpha-D-ribosyl-transferase activity, OPRT activity 
Catalysis of the reaction: orotidine 5'-phosphate + diphosphate = orotate + 5-phospho-alpha-D-ribose 1-diphosphate. [EC:2.4.2.10]
National Institutes of Health

Topic mentions per year

Topic mentions per year

1959-2017
02419592017

Related topics

Related topics

1 relation
OROTATE PHOSPHORIBOSYLTRANSFERASE

Related mentions per year

Related mentions per year

1959-2018
1960198020002020
orotate phosphoribosyltransferase activity
OROTATE PHOSPHORIBOSYLTRANSFERASE

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2009
2009
Kinetic benefits and thermal stability of orotate phosphoribosyltransferase and orotidine 5'-monophosphate decarboxylase enzyme complex in human malaria parasite Plasmodium falciparum.
We have previously shown that orotate phosphoribosyltransferase (OPRT) and orotidine 5'-monophosphate decarboxylase (OMPDC) in… (More)
  • figure 1
  • table 3
  • table 1
  • table 2
  • figure 2
Is this relevant?
2008
2008
Decreased orotate phosphoribosyltransferase activity produces 5-fluorouracil resistance in a human gastric cancer cell line.
To elucidate the mechanism of resistance to 5-fluorouracil (5-FU) in human gastric cancer cells, we established a cell line MKN45… (More)
  • figure 1
  • table I
  • figure 2
  • figure 4
  • figure 5
Is this relevant?
2008
2008
Two Arabidopsis ADP-glucose pyrophosphorylase large subunits (APL1 and APL2) are catalytic.
ADP-glucose (Glc) pyrophosphorylase (ADP-Glc PPase) catalyzes the first committed step in starch biosynthesis. Higher plant ADP… (More)
  • figure 1
  • table I
  • figure 2
  • table II
  • figure 3
Is this relevant?
2007
2007
Occurrence of multiple, independent gene fusion events for the fifth and sixth enzymes of pyrimidine biosynthesis in different eukaryotic groups.
The genes encoding orotate phosphoribosyltransferase (OPRT) and orotidine-5'-monophosphate decarboxylase (OMPDC), the fifth and… (More)
Is this relevant?
2004
2004
Prognostic significance of orotate phosphoribosyltransferase activity in bladder carcinoma.
BACKGROUND 5-Fluorouracil (5-FU), an antitumor agent, is used clinically against a variety of malignancies, including bladder… (More)
Is this relevant?
2004
2004
Significance of orotate phosphoribosyltransferase activity in renal cell carcinoma.
PURPOSE The anticancer agent 5-fluorouracil (5-FU) is clinically used against various cancers, including renal cell carcinoma… (More)
Is this relevant?
2004
2004
Both subunits of ADP-glucose pyrophosphorylase are regulatory.
The allosteric enzyme ADP-Glc pyrophosphorylase (AGPase) catalyzes the synthesis of ADP-Glc, a rate-limiting step in starch… (More)
Is this relevant?
1999
1999
Effects of C-terminal deletion on the activity and thermostability of orotate phosphoribosyltransferase from Thermus thermophilus.
To investigate the role of the C-terminal region on the activity and thermostability of orotate phosphoribosyltransferase… (More)
Is this relevant?
1976
1976
A rapid, enzymatic assay for measurement of inorganic pyrophosphate in biological samples.
An enzymatic assay for measurement of inorganic pyrophosphate (PPi) in biological samples is described using the UDPG… (More)
Is this relevant?
1968
1968
Metabolic Cooperation between Genetically Marked Human Fibroblasts in Tissue Culture
GENETIC variants of several mammalian cell lines which are not able to incorporate preformed purine or nucleoside into the cell's… (More)
Is this relevant?