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org 24598

Known as: R-(-)-N-methyl-N-(3-(4-trifluoromethyl)phenoxy)-3-phenyl-propylglycine lithium salt, org24598 
 
National Institutes of Health

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2020
2020
Frontocortical NMDA receptors are pivotal in regulating cognition and mood, are hypofunctional in schizophrenia, and may… Expand
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2012
2012
Extracellular glycine modulates accumbal dopamine levels as well as ethanol-induced dopamine overflow. Glycine availability is… Expand
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2012
2012
Cognitive enhancers that act by increasing glycine transmission might be useful adjuncts to cocaine-cue extinction training to… Expand
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2011
2011
Glycine transporter-1 (GlyT-1) in glial cells regulates extracellular levels of glycine, which acts as an obligatory co-agonist… Expand
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2011
2011
Alcohol addiction and abuse is a main contributor to the global burden of disease and is a high public health priority. Alcohol… Expand
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Highly Cited
2004
Highly Cited
2004
Using whole cell voltage clamp recordings from lamina X neurones in rat spinal cord slices, we investigated the effect of glycine… Expand
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2004
2004
In this study we have employed the selective glycine transporter-1 (GlyT-1) and GlyT-2 transporter inhibitors R-(-)-N-methyl-N-[3… Expand
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Highly Cited
2003
Highly Cited
2003
BACKGROUND Neonatal ventral hippocampal (NVH) lesions in rats induce behavioral abnormalities at adulthood thought to simulate… Expand
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2001
2001
The discovery of Org 24598, one of the first potent and selective inhibitors of the glycine transporter is discussed. In vitro… Expand
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2000
2000
The conformational analysis of peptides containing a single alpha,alpha-di-n-propylglycine (Dpg) residue incorporated into valine… Expand
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