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orbofiban

Known as: N(((3)-1-(p-amidino-phenyl)-2-oxo-3-pyrrolidinyl)carbamoyl)-beta-alanine,ethyl ester, monoacetate quadrantihydrate, orofiban 
National Institutes of Health

Papers overview

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Highly Cited
2004
Highly Cited
2004
Background: Lower admission heart rate (HR) is known to predict favorable outcome in ST‐elevation acute myocardial infarction… Expand
Highly Cited
2003
Highly Cited
2003
Background—Monocyte chemoattractant protein-1 (MCP-1) is a chemokine responsible for the recruitment of monocytes to sites of… Expand
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Highly Cited
2003
Highly Cited
2003
BACKGROUND Cerebrovascular accidents (CVAs), transient ischemic attacks (TIAs), and peripheral arterial disease (PAD) frequently… Expand
Highly Cited
2001
Highly Cited
2001
BACKGROUND Brain (B-type) natriuretic peptide is a neurohormone synthesized predominantly in ventricular myocardium. Although the… Expand
Highly Cited
2000
Highly Cited
2000
BACKGROUND Although intravenous glycoprotein IIb/IIIa inhibitors are beneficial in patients with acute coronary syndromes… Expand
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Highly Cited
2000
Highly Cited
2000
Patients receiving the oral glycoprotein IIb-IIIa inhibitor orbofiban in the OPUS -TIMI 16 trial had a paradoxical increase in… Expand
Highly Cited
2000
Highly Cited
2000
The platelet integrin glycoprotein (GP) IIb/IIIa, which mediates platelet aggregation, has been the target for novel antiplatelet… Expand
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Highly Cited
2000
Highly Cited
2000
OBJECTIVE To determine whether glycoprotein (GP) IIb-IIIa inhibitors can paradoxically augment activation of platelets… Expand
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Highly Cited
2000
Highly Cited
2000
OBJECTIVES The study was done to determine the role of partial agonist activity in the lack of effectiveness of the oral GPIIb… Expand
Review
1998
Review
1998
Abbreviations: ACE trial 5 Acetylsalicylic Acid and Carotid Endarterectomy; ADP 5 adenosine diphosphate; AMP 5 adenosine… Expand
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