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National Institutes of Health
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OncoHist®, an rh Histone 1.3, Is Cytotoxic to Acute Myeloid Leukemia Cells and Results in Altered Downstream Signaling
Corpus ID: 89484994
Acute myeloid leukemia (AML) is a heterogeneous myeloid stem cell disorder; subtypes, which can be defined histologically…
Infrared spectroscopy for biopharmaceutical protein analysis.
Peter C Gross
Journal of pharmaceutical and biomedical analysis
Corpus ID: 21727317
A mid-infrared transmission spectroscopic method with the possibility of high sample throughput was developed and validated on…
A Phase I/II Dose Escalation Trial of ONCOHIST® (Recombinant Human Histone H1.3) in Patients with Relapsed or Refractory Acute Myeloid Leukemia.
Corpus ID: 78805344
Background: Histone H1.3 suppresses tumor growth of leukemic cells in vitro, ex vivo and in animal models. To evaluate toxicity…
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