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onapristone

Known as: 11 beta-(4-dimethylaminophenyl)-17 alpha-hydroxy-17 beta-(3-hydroxypropyl)-13 alpha-methyl-4,9-gonadien-3-one, Estra-4,9-dien-3-one, 11-(4-(dimethylamino)phenyl)-17-hydroxy-17-(3-hydroxypropyl)-, (11beta,13alpha,17alpha)- 
National Institutes of Health

Related topics

Related topics

6 relations

Broader (4)

Antineoplastic AgentsFertility Agents, FemaleGonanesHormone Antagonists

Narrower (2)

ZK 299ZK 98.299

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2014
2014
The antiprogestins mifepristone and onapristone reduce cell proliferation in the canine mammary carcinoma cell line CMT-U27.
Canine mammary tumours (CMTs) represent nearly half of all tumours in female dogs and some 50% have malignant behaviour. Simple… 
2003
2003
Effects of an Antiprogestin Onapristone on the Endometrium of Bonnet Monkeys: Morphometric and Ultrastructural Studies
Abstract Our previous studies demonstrated the ability of low doses of antiprogestin ZK 98.299 (onapristone) to inhibit fertility… 
2001
2001
Medroxyprogesterone acetate enhances in vivo and in vitro antibody production
In the present study we examine the effects of medroxyprogesterone acetate (MPA) on the specific antibody secretion to T… 
1997
1997
The possible use of antiprogestins for contraception.
BACKGROUND A number of compounds, antiprogestins, e.g. mifepristone, onapristone and lilopristone, have been developed which… 
1996
1996
The effects of post-ovulatory administration of onapristone on the developmnent of a secretory endometrium.
The purpose of this study was to assess the ability of the anti-progestin onapristone administered in the immediate post… 
1994
1994
Effect of the antiprogestin onapristone on follicular growth in women.
The effects of the antiprogestin onapristone on the menstrual cycle were assessed in surgically sterilized volunteer women. The… 
1993
1993
Effects of onapristone, tamoxifen and ICI 182780 on uterine prostaglandin production and luteal function in nonpregnant guinea-pigs.
Onapristone (a progesterone antagonist) or ICI 182780 (an oestrogen antagonist) administered to guinea-pigs on days 11-14 of the… 
1993
1993
Effects of onapristone on uterine prostaglandin production and plasma progesterone concentrations in guinea-pigs during early and mid-pregnancy.
Onapristone (a progesterone receptor antagonist) administered to guinea-pigs on days 11-14 of pregnancy had no effect on uterine… 
1990
1990
Tumor-inhibiting potential of ZK 112.993, a new progesterone antagonist, in hormone-sensitive, experimental rodent and human mammary tumors.
The progesterone antagonists Onapristone (ZK 98.299) and Mifepristone (RU 486) proved to be strong inhibitors of various rodent… 
1989
1989
Failure of two progesterone antagonists, mifepristone and onapristone, to affect luteal activity in lactating rats.
The progesterone antagonists, mifepristone (RU-38,486) and onapristone (ZK-98,299), given as 2 mg daily, did not markedly affect… 
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