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omega-Agatoxin IVA

Known as: omega-Aga-IVA, IVA, omega-Agatoxin, omega-Agatoxin IVA [Chemical/Ingredient] 
A neuropeptide toxin from the venom of the funnel web spider, Agelenopsis aperta. It inhibits CALCIUM CHANNELS, P-TYPE by altering the voltage… Expand
National Institutes of Health

Papers overview

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Highly Cited
2007
Highly Cited
2007
We used a preparation of acutely dissociated neurons to quantify the ionic currents driving the spontaneous firing of substantia… Expand
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Highly Cited
2002
Highly Cited
2002
Gabapentin and pregabalin (S-(+)-3-isobutylgaba) produced concentration-dependent inhibitions of the K(+)-induced [Ca(2+)](i… Expand
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Highly Cited
2002
Highly Cited
2002
Calcium entry into mature erythrocytes (red blood cells; RBCs) is associated with multiple changes in cell properties. At low… Expand
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Highly Cited
2000
Highly Cited
2000
Multiple types of high-voltage-activated Ca(2+) channels trigger neurotransmitter release at the mammalian central synapse. Among… Expand
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1998
1998
Apolipoprotein E (apoE) is the major apolipoprotein in the brain and is known for its important role in plasticity and… Expand
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Highly Cited
1995
Highly Cited
1995
The manner in which presynaptic Ca2+ influx controls the release of neurotransmitter was investigated at the granule cell to… Expand
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Highly Cited
1995
Highly Cited
1995
1. Dendrites of rat neocortical layer V pyramidal neurons were loaded with the Ca2+ indicator dye Calcium Green-1 (CG-1) or fluo… Expand
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Highly Cited
1993
Highly Cited
1993
The regulation of excitation-secretion coupling by Ca2+ channels is a fundamental property of the nerve terminal. Peptide toxins… Expand
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Highly Cited
1992
Highly Cited
1992
The peptide toxin omega-Aga-IVA blocked P-type Ca2+ channel current in rat Purkinje neurons (KD approximately 2 nM) but had no… Expand
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Highly Cited
1992
Highly Cited
1992
Voltage-dependent calcium channels mediate calcium entry into neurons, which is crucial for many processes in the brain including… Expand
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