omega-Agatoxin IVA

Known as: omega-Aga-IVA, IVA, omega-Agatoxin, omega-Agatoxin IVA [Chemical/Ingredient] 
A neuropeptide toxin from the venom of the funnel web spider, Agelenopsis aperta. It inhibits CALCIUM CHANNELS, P-TYPE by altering the voltage… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1992-2013
051019922013

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2007
Highly Cited
2007
We used a preparation of acutely dissociated neurons to quantify the ionic currents driving the spontaneous firing of substantia… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 5
  • figure 4
Is this relevant?
1996
1996
Because the P- and Q-type Ca2+ channel antagonist omega-agatoxin IVA inhibits glutamate release, agatoxin-related drugs could… (More)
Is this relevant?
Highly Cited
1995
Highly Cited
1995
The manner in which presynaptic Ca2+ influx controls the release of neurotransmitter was investigated at the granule cell to… (More)
  • figure 1
  • figure 2
  • figure 4
  • figure 5
  • figure 6
Is this relevant?
1995
1995
This investigation assessed the ability of a variety of calcium channel blocking peptides to block synaptic transmission in the… (More)
Is this relevant?
1995
1995
1. The effects were studied of the central neurone P-type Ca2+ channel blockers, omega-agatoxin IVA, omega-conotoxin MVIIC… (More)
Is this relevant?
Highly Cited
1993
Highly Cited
1993
Synaptic transmission is mediated by calcium entry through voltage-dependent calcium channels in presynaptic nerve terminals… (More)
Is this relevant?
Highly Cited
1993
Highly Cited
1993
Transcripts for the class A Ca2+ channel alpha 1 subunit (also known as BI) are present at high levels in many parts of the… (More)
Is this relevant?
Highly Cited
1993
Highly Cited
1993
N-type calcium channels play a dominant role in controlling synaptic transmission in many peripheral neurons. Transmitter release… (More)
Is this relevant?
Highly Cited
1992
Highly Cited
1992
The peptide toxin omega-Aga-IVA blocked P-type Ca2+ channel current in rat Purkinje neurons (KD approximately 2 nM) but had no… (More)
Is this relevant?
Highly Cited
1992
Highly Cited
1992
Voltage-dependent calcium channels mediate calcium entry into neurons, which is crucial for many processes in the brain including… (More)
Is this relevant?