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omalizumab

Known as: Immunoglobulin G, anti-(human immunoglobulin E Fc region)(human-mouse monoclonal E25 clone pSVIE26 gamma-chain), disulfide with human-mouse monoclonal E25 clone pSVIE26 kappa-chain, dimer, Omalizumab [Chemical/Ingredient], Ig gamma-1 chain C region 
An anti-IgE, recombinant, humanized monoclonal antibody which specifically binds to the C epsilon3 domain of IMMUNOGLOBULIN E, the site of high… Expand
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2019
Review
2019
  • W. Busse
  • Allergology international : official journal of…
  • 2019
  • Corpus ID: 73480061
Asthma is a heterogeneous disease with considerable variability noted in disease severity, patterns of airway inflammation, and… Expand
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Review
2018
Review
2018
BACKGROUND The present review is part of the ESCMID Study Group for Infections in Compromised Hosts (ESGICH) Consensus Document… Expand
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Highly Cited
2013
Highly Cited
2013
BACKGROUND Many patients with chronic idiopathic urticaria (also called chronic spontaneous urticaria) do not have a response to… Expand
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Highly Cited
2013
Highly Cited
2013
RATIONALE For many patients with asthma, allergic airway inflammation is primarily a Th2-weighted process; however, heterogeneity… Expand
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Highly Cited
2011
Highly Cited
2011
BACKGROUND Research has underscored the effects of exposure and sensitization to allergens on the severity of asthma in inner… Expand
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Highly Cited
2005
Highly Cited
2005
Background:  Patients with severe persistent asthma who are inadequately controlled despite Global Initiative for Asthma (GINA… Expand
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Highly Cited
2004
Highly Cited
2004
IgE plays an important role in allergic asthma. We hypothesized that reducing IgE in the airway mucosa would reduce airway… Expand
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Highly Cited
2001
Highly Cited
2001
BACKGROUND A recombinant humanized anti-IgE mAb, omalizumab, forms complexes with free IgE, blocking its interaction with mast… Expand
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Highly Cited
2001
Highly Cited
2001
The clinical benefit and steroid-sparing effect of treatment with the anti-immunoglobulin-E (IgE) antibody, omalizumab, was… Expand
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Highly Cited
2001
Highly Cited
2001
BACKGROUND AND OBJECTIVE There seems to be a strong causal relationship between allergy and the origins of asthma. Susceptibility… Expand
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