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olomoucine II

 
National Institutes of Health

Papers overview

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2013
2013
Cyclin-dependent kinase inhibitors (CDKi) have high potential applicability in anticancer therapy, but various aspects of their… Expand
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2013
2013
Purine cyclin-dependent kinase inhibitors have been recognized as promising candidates for the treatment of various cancers… Expand
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2012
2012
Inhibition of cyclin-dependent kinases by specific small molecules, purine cyclin-dependent kinase inhibitors (CDKi), has become… Expand
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2011
2011
Aristolochia manshuriensis has been used for centuries in Chinese medicinal system for their versatile medicinal uses. Recent… Expand
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Highly Cited
2010
Highly Cited
2010
Embryonic stem cells (ESCs) proliferate rapidly and have a unique cell-cycle structure with a very short G1 phase. Previous… Expand
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2010
2010
Background: Olomoucine II, the most recent derivative of roscovitine, is an exceptionally potent pharmacological inhibitor of… Expand
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2010
2010
Nine geranylated flavanones isolated from the fruits of Paulownia tomentosa (4-12) and two from the roots of Morus alba (13 and… Expand
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2009
2009
Olomoucine II is a cyclin-dependent kinase inhibitor and a potential antineoplastic agent because it can arrest animal cell… Expand
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Highly Cited
2005
Highly Cited
2005
Abstract.The study describes the protein kinase selectivity profile, as well as the binding mode of olomoucine II in the… Expand
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Highly Cited
2002
Highly Cited
2002
Based on our previous experiences with synthesis of purines, novel 2,6,9-trisubstituted purine derivatives were prepared and… Expand