oligodendrocyte differentiation

The process in which a relatively unspecialized cell acquires the specialized features of an oligodendrocyte. An oligodendrocyte is a type of glial… (More)
National Institutes of Health

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Highly Cited
2013
Highly Cited
2013
The lack of therapies for progressive multiple sclerosis highlights the need to understand the regenerative process of… (More)
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Review
2010
Review
2010
Despite the importance of myelin for the rapid conduction of action potentials, the molecular bases of oligodendrocyte… (More)
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Highly Cited
2010
Highly Cited
2010
MicroRNAs (miRNAs) regulate various biological processes, but evidence for miRNAs that control the differentiation program of… (More)
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Highly Cited
2006
Highly Cited
2006
Glial fibrillary acidic protein (GFAP)-positive astrocytes (type B cells) in the subventricular zone (SVZ) generate large numbers… (More)
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Highly Cited
2006
Highly Cited
2006
To better understand the molecular mechanisms governing oligodendrocyte (OL) differentiation, we have used gene profiling to… (More)
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Highly Cited
2005
Highly Cited
2005
The control of myelination by oligodendrocytes in the CNS is poorly understood. Here we show that LINGO-1 is an important… (More)
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Highly Cited
2004
Highly Cited
2004
It has become apparent that chromatin modification plays a critical role in the regulation of cell-type-specific gene expression… (More)
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Highly Cited
2001
Highly Cited
2001
Olig2, a basic helix-loop-helix (bHLH) transcription factor, is expressed in a restricted domain of the spinal cord ventricular… (More)
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Highly Cited
2001
Highly Cited
2001
Oligodendrocytes are derived from glial precursors that arise from the ventral neural tube early in development. In the… (More)
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Highly Cited
1998
Highly Cited
1998
In this study, we show that oligodendrocyte differentiation is powerfully inhibited by activation of the Notch pathway… (More)
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