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obatoclax mesylate
Known as:
2-(2-[(3,5-Dimethyl-1H-pyrrol-2-yl)methylidene]-3-methoxy-2H-pyrrol-5-yl)-1H-indole Monomethanesulfonate
The mesylate salt of obatoclax, a synthetic small-molecule inhibitor of the bcl-2 family of proteins with potential pro-apoptotic and antineoplastic…
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National Institutes of Health
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3 relations
GX15-070MS
NCIt Antineoplastic Agent Terminology
obatoclax
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2016
2016
Phase I study of obatoclax mesylate (GX15–070MS), a bcl-2 antagonist, plus topotecan in relapsed small cell lung carcinoma and other solid tumors
Andrew B. Brown
,
C. Rudin
,
+7 authors
L. Krug
2016
Corpus ID: 263520036
3504 Background: Bcl-2 is a rational target in SCLC since it is overexpressed in 60%-90% of tumors and may play a role in…
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2010
2010
Gateways to clinical trials.
A. Tomillero
,
M. A. Moral
Methods and Findings in Experimental and Clinical…
2010
Corpus ID: 43025264
(-)-Epigallocatechin gallate, Abafungin, ACE-031, Adapalene/benzoyl peroxide, AE-37, Aflibercept, AGS-003, Albiglutide…
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2009
2009
Gateways to clinical trials.
A. Tomillero
,
M. A. Moral
Methods and Findings in Experimental and Clinical…
2009
Corpus ID: 44829782
ABT-869, Acadesine, Acetylsalicylic acid/omeprazole, Adefovir, Adefovir dipivoxil, AEG-35156, Agatolimod sodium, Albiglutide…
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