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nuclear receptor subfamily 1, group H, member 2
Known as:
LXRbeta Protein
, Liver X Receptor Beta
, Liver X Receptor-Beta
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A liver X receptor that is ubiquitously expressed. Loss of LXR-beta function is associated with an increase in the expression of UNCOUPLING PROTEIN 1…
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National Institutes of Health
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Related topics
Related topics
2 relations
Broader (1)
Liver X Receptors
NR1H2 gene
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Review
2017
Review
2017
Rapid screening for lipid storage disorders using biochemical markers. Expert center data and review of the literature.
M. Voorink-Moret
,
S. Goorden
,
+7 authors
F. Vaz
Molecular Genetics and Metabolism
2017
Corpus ID: 25862267
2013
2013
Explorer 11-Hydroxysteroid dehydrogenase type 1 contributes to the balance between 7-keto-and 7-hydroxy-oxysterols in vivo
T. Mitić
,
S. Shave
,
+7 authors
Ruth Andrewa
2013
Corpus ID: 10390157
11b-Hydroxysteroid dehydrogenase 1 (11bHSD1; EC 1.1.1.146) generates active glucocorticoids from inert 11-keto metabolites…
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2011
2011
Liver X Receptor β (LXRβ) Interacts Directly with ATP-binding Cassette A1 (ABCA1) to Promote High Density Lipoprotein Formation during Acute Cholesterol Accumulation*
M. Hozoji-Inada
,
Youichi Munehira
,
K. Nagao
,
N. Kioka
,
K. Ueda
Journal of Biological Chemistry
2011
Corpus ID: 29302919
Cells have evolved multiple mechanisms for maintaining cholesterol homeostasis, and, among these, ATP-binding cassette protein A1…
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2010
2010
Neuropathologic and Biochemical Changes During Disease Progression in Liver X Receptor &bgr;−/− Mice, A Model of Adult Neuron Disease
P. Bigini
,
K. Steffensen
,
+8 authors
J. Gustafsson
Journal of Neuropathology and Experimental…
2010
Corpus ID: 16502454
In amyotrophic lateral sclerosis (ALS), there is selective degeneration of motor neurons that leads to paralysis and death…
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2010
2010
Liver X receptor β and thyroid hormone receptor α in brain cortical layering
Xin-jie Tan
,
Xiao-Tang Fan
,
+4 authors
J. Gustafsson
Proceedings of the National Academy of Sciences…
2010
Corpus ID: 20924973
In the past year, two members of the nuclear receptor family, liver X receptor β (LXRβ) and thyroid hormone receptor α (TR…
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Highly Cited
2009
Highly Cited
2009
Serum cholesterol and expression of ApoAI, LXRβ and SREBP2 in vitamin D receptor knock-out mice
Jing-Huan Wang
,
T. Keisala
,
T. Solakivi
,
A. Minasyan
,
A. Kalueff
,
P. Tuohimaa
Journal of Steroid Biochemistry and Molecular…
2009
Corpus ID: 35303861
Highly Cited
2008
Highly Cited
2008
Liver X receptor β (LXRβ): A link between β-sitosterol and amyotrophic lateral sclerosis–Parkinson's dementia
Hyun-jin Kim
,
Xiaotang Fan
,
+4 authors
J. Gustafsson
Proceedings of the National Academy of Sciences…
2008
Corpus ID: 5281112
Administration of β-sitosterol (42 mg/kg per day) for 3 weeks to 8-month-old male LXRβ−/− mice resulted in the death of motor…
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Highly Cited
2007
Highly Cited
2007
Liver X Receptor Activation Enhances Cholesterol Loss from the Brain, Decreases Neuroinflammation, and Increases Survival of the NPC1 Mouse
J. Repa
,
Hao Li
,
+4 authors
J. Dietschy
Journal of Neuroscience
2007
Corpus ID: 166924
Although cholesterol is a major component of the CNS, there is little information on how or whether a change in sterol flux…
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2003
2003
Miniaturization of cell-based beta-lactamase-dependent FRET assays to ultra-high throughput formats to identify agonists of human liver X receptors.
J. Chin
,
A. Adams
,
+7 authors
L. Mitnaul
Assay and drug development technologies
2003
Corpus ID: 11201265
Activation of liver X receptors (LXRs) induces reverse cholesterol transport and increases high-density lipoprotein cholesterol…
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2002
2002
Regulation of ALK-1 Signaling by the Nuclear Receptor LXRβ*
J. Mo
,
S. Fang
,
Wei Chen
,
G. Blobe
Journal of Biological Chemistry
2002
Corpus ID: 41491907
The transforming growth factor β (TGF-β) receptor, ALK-1, is expressed specifically on endothelial cells and is essential for…
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