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noxiustoxin

Known as: NxTX protein, C noxius, alpha-KTx 2.1, C noxius, toxin II-11 
 
National Institutes of Health

Related topics

Related topics

2 relations

Broader (2)

Potassium Channel BlockersScorpion Venoms

Papers overview

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Highly Cited
1994
Highly Cited
1994
Pharmacological characterization of five cloned voltage-gated K+ channels, types Kv1.1, 1.2, 1.3, 1.5, and 3.1, stably expressed in mammalian cell lines.
We have analyzed the biophysical and pharmacological properties of five cloned K+ (Kv) channels (Kv1.1, Kv1.2, Kv1.3, Kv1.5, and… Expand
Highly Cited
1993
Highly Cited
1993
Voltage-gated potassium channels regulate calcium-dependent pathways involved in human T lymphocyte activation
The role that potassium channels play in human T lymphocyte activation has been investigated by using specific potassium channel… Expand
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Highly Cited
1993
Highly Cited
1993
Purification, characterization, and biosynthesis of margatoxin, a component of Centruroides margaritatus venom that selectively inhibits voltage-dependent potassium channels.
A novel peptidyl inhibitor of K+ channels has been purified to homogeneity from venom of the new world scorpion Centruroides… Expand
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Highly Cited
1993
Highly Cited
1993
Calcium-activated potassium channels in resting and activated human T lymphocytes. Expression levels, calcium dependence, ion selectivity, and pharmacology
Ca(2+)-activated K+[K(Ca)] channels in resting and activated human peripheral blood T lymphocytes were characterized using… Expand
Highly Cited
1992
Highly Cited
1992
Selective blockers of voltage-gated K+ channels depolarize human T lymphocytes: mechanism of the antiproliferative effect of charybdotoxin.
Charybdotoxin (ChTX), a K+ channel blocker, depolarizes human peripheral T lymphocytes and renders them insensitive to activation… Expand
Review
1989
Review
1989
Toxins in the characterization of potassium channels
Several recently characterized toxins (apamin, charybdotoxin, dendrotoxin and noxiustoxin) are proving invaluable for… Expand
Highly Cited
1989
Highly Cited
1989
Charybdotoxin blocks voltage-gated K+ channels in human and murine T lymphocytes
A variety of scorpion venoms and purified toxins were tested for effects on ion channels in human T lymphocytes, a human T… Expand
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1988
1988
Charybdotoxin and noxiustoxin, two homologous peptide inhibitors of the K+(Ca2+) channel
We show that noxiustoxin (NTX), like charybdotoxin (CTX) described by others, affects Ca2+‐activated K+ channels of skeletal… Expand
Highly Cited
1988
Highly Cited
1988
Purification and characterization of a unique, potent inhibitor of apamin binding from Leiurus quinquestriatus hebraeus venom.
An inhibitor of apamin binding has been purified to homogeneity in three chromatographic steps from the venom of the scorpion… Expand
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1986
1986
Noxiustoxin, a short-chain toxin from the Mexican scorpion Centruroides noxius, induces transmitter release by blocking K+ permeability
Noxiustoxin (NTX), a 39 amino acid peptide purified from the venom of the Mexican scorpion Centruroides noxius, has been shown to… Expand
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