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noxiustoxin

Known as: NxTX protein, C noxius, alpha-KTx 2.1, C noxius, toxin II-11 
 
National Institutes of Health

Topic mentions per year

Topic mentions per year

1953-2016
024619532015

Related topics

Related topics

2 relations

Broader (2)

Potassium Channel BlockersScorpion Venoms

Related mentions per year

Related mentions per year

1946-2018
19401960198020002020
noxiustoxin
Scorpion Venoms
Potassium Channel Blockers

Papers overview

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2002
2002
From noxiustoxin to scorpine and possible transgenic mosquitoes resistant to malaria.
Scorpion venom contains different types of peptides toxic to a variety of organisms whose molecular targets have been described… (More)
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1998
1998
Site directed mutants of Noxiustoxin reveal specific interactions with potassium channels.
Several site directed mutations were introduced into a synthetic Noxiustoxin (NTX) gene. Alanine scanning of the nonapeptide at… (More)
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1995
1995
Determination of the three-dimensional solution structure of noxiustoxin: analysis of structural differences with related short-chain scorpion toxins.
The 3D structure of noxiustoxin, the first identified scorpion toxin acting on K+ channels, has been elucidated by NMR and… (More)
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Highly Cited
1994
Highly Cited
1994
Pharmacological characterization of five cloned voltage-gated K+ channels, types Kv1.1, 1.2, 1.3, 1.5, and 3.1, stably expressed in mammalian cell lines.
We have analyzed the biophysical and pharmacological properties of five cloned K+ (Kv) channels (Kv1.1, Kv1.2, Kv1.3, Kv1.5, and… (More)
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Highly Cited
1993
Highly Cited
1993
Calcium-activated potassium channels in resting and activated human T lymphocytes. Expression levels, calcium dependence, ion selectivity, and pharmacology
Ca(2+)-activated K+[K(Ca)] channels in resting and activated human peripheral blood T lymphocytes were characterized using… (More)
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Highly Cited
1993
Highly Cited
1993
Purification, characterization, and biosynthesis of margatoxin, a component of Centruroides margaritatus venom that selectively inhibits voltage-dependent potassium channels.
A novel peptidyl inhibitor of K+ channels has been purified to homogeneity from venom of the new world scorpion Centruroides… (More)
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Highly Cited
1993
Highly Cited
1993
Voltage-gated potassium channels regulate calcium-dependent pathways involved in human T lymphocyte activation
The role that potassium channels play in human T lymphocyte activation has been investigated by using specific potassium channel… (More)
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Highly Cited
1992
Highly Cited
1992
Selective blockers of voltage-gated K+ channels depolarize human T lymphocytes: mechanism of the antiproliferative effect of charybdotoxin.
Charybdotoxin (ChTX), a K+ channel blocker, depolarizes human peripheral T lymphocytes and renders them insensitive to activation… (More)
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1992
1992
Kaliotoxin, a novel peptidyl inhibitor of neuronal BK-type Ca(2+)-activated K+ channels characterized from Androctonus mauretanicus mauretanicus venom.
A peptidyl inhibitor of the high conductance Ca(2+)-activated K+ channels (KCa) has been purified to homogeneity from the venom… (More)
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1988
1988
Charybdotoxin and noxiustoxin, two homologous peptide inhibitors of the K+ (Ca2+) channel.
We show that noxiustoxin (NTX), like charybdotoxin (CTX) described by others, affects Ca2+-activated K+ channels of skeletal… (More)
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