noviose

 
National Institutes of Health

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2014
2014
The rare carbohydrate L-(+)-noviose was synthesized from enantiomerically pure L-lactate. The configuration at C-4 was… (More)
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2013
2013
Abstract Simplified aminocoumarin analogues, either noviosylated or simple basic heterocycle attached 3-amido-coumarin compounds… (More)
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2009
2009
We evaluated whether inhibition of heat shock protein 90 (hsp90) function by novobiocin derivatives could induce the degradation… (More)
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2007
2007
Selective hsp90 inhibitors simultaneously destabilize and deplete key signaling proteins involved in cell proliferation and… (More)
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2006
2006
Abstract Noviose, the rare sugar moiety present in novobiocin, is an important antimicrobial and antitumor agent that has been… (More)
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2006
2006
Novobiocin and clorobiocin are gyrase inhibitors produced by Streptomyces strains. Structurally, the two compounds differ only by… (More)
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2004
2004
Noviose is a key synthon for the construction of novobiocin, a clinically useful antitumor agent that has been shown to inhibit… (More)
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2000
2000
A new series of coumarin inhibitors of DNA gyrase B bearing a N-propargyloxycarbamate at C-3' of various 5',5'-dialkylnoviose… (More)
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1998
1998
Abstract Noviose ( 1 ), the sugar moiety of the antibiotic Novobiocin 1 , has been synthesized enantioselectively from the… (More)
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1986
1986
Nach Schutz der C-1- bis C-3-Position wird L-Rhamnose (1) zur Methyl-2,3-O-isopropyliden-α-L-rhamnofuranosid-5-ulose (3) oxidiert… (More)
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