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noviose

 
National Institutes of Health

Papers overview

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2015
2015
The first enantioselective total synthesis of fidaxomicin, also known as tiacumicin B or lipiarmycin A3, is reported. This novel… Expand
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2010
2010
NovP is an S-adenosyl-l-methionine-dependent O-methyltransferase that catalyzes the penultimate step in the biosynthesis of the… Expand
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Highly Cited
2009
Highly Cited
2009
We evaluated whether inhibition of heat shock protein 90 (hsp90) function by novobiocin derivatives could induce the degradation… Expand
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Highly Cited
2007
Highly Cited
2007
Selective hsp90 inhibitors simultaneously destabilize and deplete key signaling proteins involved in cell proliferation and… Expand
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2006
2006
ABSTRACT Novobiocin and clorobiocin are gyrase inhibitors produced by Streptomyces strains. Structurally, the two compounds… Expand
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2005
2005
Aminocoumarin antibiotics are highly potent inhibitors of bacterial gyrase and represent a class of antibiotics that are very… Expand
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2004
2004
Noviose is a key synthon for the construction of novobiocin, a clinically useful antitumor agent that has been shown to inhibit… Expand
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Highly Cited
2000
Highly Cited
2000
A new series of coumarin inhibitors of DNA gyrase B bearing a N-propargyloxycarbamate at C-3' of various 5',5'-dialkylnoviose… Expand
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1986
1986
Novobiocin inhibits semiconservative DNA replication in procaryotes and more specifically DNA gyrase, an enzyme essential for DNA… Expand
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1962
1962
 
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