noviose

 
National Institutes of Health

Related topics

Related topics

1 relation

Broader (1)

Monosaccharides

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2014
2014
Metathesis-Based De Novo Synthesis of Noviose
The rare carbohydrate L-(+)-noviose was synthesized from enantiomerically pure L-lactate. The configuration at C-4 was… (More)
Is this relevant?
2013
2013
Simplified aminocoumarin analogues as anticancer agents: Amino isosteric replacement in the noviose moiety resulted in substantial enhancement of antiproliferative activity
Abstract Simplified aminocoumarin analogues, either noviosylated or simple basic heterocycle attached 3-amido-coumarin compounds… (More)
Is this relevant?
2009
2009
Antiproliferative and apoptotic activities of tosylcyclonovobiocic acids as potent heat shock protein 90 inhibitors in human cancer cells.
We evaluated whether inhibition of heat shock protein 90 (hsp90) function by novobiocin derivatives could induce the degradation… (More)
  • table 1
  • figure 1
  • table 2
  • figure 2
  • figure 3
Is this relevant?
2007
2007
New novobiocin analogues as antiproliferative agents in breast cancer cells and potential inhibitors of heat shock protein 90.
Selective hsp90 inhibitors simultaneously destabilize and deplete key signaling proteins involved in cell proliferation and… (More)
Is this relevant?
2006
2006
Enantiospecific synthesis of (−)-d-noviose from (−)-pantolactone
Abstract Noviose, the rare sugar moiety present in novobiocin, is an important antimicrobial and antitumor agent that has been… (More)
Is this relevant?
2006
2006
Structure-activity relationships of aminocoumarin-type gyrase and topoisomerase IV inhibitors obtained by combinatorial biosynthesis.
Novobiocin and clorobiocin are gyrase inhibitors produced by Streptomyces strains. Structurally, the two compounds differ only by… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Is this relevant?
2004
2004
Synthesis of (-)-noviose from 2,3-O-isopropylidene-D-erythronolactol.
Noviose is a key synthon for the construction of novobiocin, a clinically useful antitumor agent that has been shown to inhibit… (More)
Is this relevant?
2000
2000
Improved antibacterial activities of coumarin antibiotics bearing 5',5'-dialkylnoviose: biological activity of RU79115.
A new series of coumarin inhibitors of DNA gyrase B bearing a N-propargyloxycarbamate at C-3' of various 5',5'-dialkylnoviose… (More)
Is this relevant?
1998
1998
ENANTIOSELECTIVE TOTAL SYNTHESIS OF (-)-D-NOVIOSE
Abstract Noviose ( 1 ), the sugar moiety of the antibiotic Novobiocin 1 , has been synthesized enantioselectively from the… (More)
Is this relevant?
1986
1986
Eine neue, einfache Synthese der Noviose
Nach Schutz der C-1- bis C-3-Position wird L-Rhamnose (1) zur Methyl-2,3-O-isopropyliden-α-L-rhamnofuranosid-5-ulose (3) oxidiert… (More)
Is this relevant?