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notochord formation

The formation of the notochord from the chordamesoderm. The notochord is composed of large cells packed within a firm connective tissue sheath and is… Expand
National Institutes of Health

Related topics

Related topics

2 relations

Broader (2)

nervous system developmentnotochord morphogenesis

Papers overview

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Highly Cited
2007
Highly Cited
2007
Live imaging and genetic analysis of mouse notochord formation reveals regional morphogenetic mechanisms.
The node and notochord have been extensively studied as signaling centers in the vertebrate embryo. The morphogenesis of these… Expand
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Highly Cited
2002
Highly Cited
2002
Dapper, a Dishevelled-associated antagonist of beta-catenin and JNK signaling, is required for notochord formation.
Dapper was isolated in a screen for proteins interacting with Dishevelled, a key factor in Wnt signaling. Dapper and Dishevelled… Expand
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Highly Cited
2002
Highly Cited
2002
Zebrafish mutants identify an essential role for laminins in notochord formation.
Basement membranes are thought to be essential for organ formation, providing the scaffold on which individual cells organize to… Expand
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Highly Cited
1998
Highly Cited
1998
Conservation of the developmental role of Brachyury in notochord formation in a urochordate, the ascidian Balocynthia roretzi.
The notochord is one of the characteristic features of the phylum Chordata. The vertebrate Brachyury gene is known to be… Expand
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Highly Cited
1996
Highly Cited
1996
Mutations affecting the formation of the notochord in the zebrafish, Danio rerio.
In a large scale screen for mutants with defects in the embryonic development of the zebrafish we identified mutations in four… Expand
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Highly Cited
1996
Highly Cited
1996
A Xenopus nodal-related gene that acts in synergy with noggin to induce complete secondary axis and notochord formation.
Using a paracrine assay to screen for signaling proteins that could respecify ectodermal tissue, we isolated a Xenopus gene… Expand
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1996
1996
Overexpression of the homeobox gene Xnot-2 leads to notochord formation in Xenopus.
Xnot-2 is a homeobox gene expressed in Spemann's organizer. Here we present evidence that microinjection of synthetic Xnot-2 mRNA… Expand
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1996
1996
Basic fibroblast growth factor induces notochord formation and the expression of As-T, a Brachyury homolog, during ascidian embryogenesis.
The tadpole larva of an ascidian develops 40 notochord cells in the center of its tail. Most of the notochord cells originate… Expand
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Highly Cited
1994
Highly Cited
1994
HNF-3 beta is essential for node and notochord formation in mouse development.
HNF-3 beta, a member of the HNF-3/fork head family of transcription factors, is expressed in the node, notochord, floor plate… Expand
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Highly Cited
1994
Highly Cited
1994
Induction of notochord during ascidian embryogenesis.
The tadpole larva of solitary ascidians has 40 notochord cells in its tail. Of these cells, 32 in the anterior and middle part of… Expand
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