norverapamil

Known as: N-demethylverapamil, alpha-(3-((2-(3,4-dimethoxyphenyl)ethyl)amino)propyl)-3,4-dimethoxy-alpha-(1-methylethyl)benzeneacetonitrile 
 
National Institutes of Health

Papers overview

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2014
2014
Drug tolerance likely represents an important barrier to tuberculosis treatment shortening. We previously implicated the… (More)
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Highly Cited
2009
Highly Cited
2009
We report the first case of sustained-release verapamil toxicity treated with Intralipid fat emulsion (IFE). Toxicity was… (More)
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2007
2007
It has been reported that verapamil and atorvastatin are inhibitors of both P-glycoprotein (P-gp) and microsomal cytochrome P450… (More)
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Highly Cited
2004
Highly Cited
2004
Verapamil inhibition of CYP3A activity results in many drug-drug interactions with CYP3A substrates, but the mechanism of… (More)
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Highly Cited
2004
Highly Cited
2004
OBJECTIVES Our objectives were to determine the content of cytochrome P450 (CYP) 3A4, CYP3A5, and P-glycoprotein and to measure… (More)
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2004
2004
We have investigated the effect of quercetin on the pharmacokinetics of verapamil and its major metabolite, norverapamil, in… (More)
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Highly Cited
2002
Highly Cited
2002
Dietary constituents (e.g., in grapefruit juice; NaCl) and phytochemicals (e.g., St. John's wort) are important agents modifying… (More)
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Highly Cited
1999
Highly Cited
1999
AIMS The present study was conducted to evaluate metabolism of the enantiomers of verapamil and norverapamil using a broad range… (More)
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Highly Cited
1998
Highly Cited
1998
OBJECTIVE To study the effects of erythromycin and verapamil on the pharmacokinetics of simvastatin, an inhibitor of 3-hydroxy-3… (More)
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1995
1995
Verapamil (CAS 52-53-9) is a calcium channel blocker with a vasodilatatory effect. Because of its significant first-pass effect… (More)
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