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norlorcainide

National Institutes of Health

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Piperidines

Papers overview

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1985
1985
Chronic lorcainide therapy for symptomatic premature ventricular complexes: efficacy, pharmacokinetics and evidence for norlorcainide antiarrhythmic effect.
Chronic premature ventricular complexes (PVCs) have been effectively suppressed by oral lorcainide as reported in previous short… 
1984
1984
Comparative Electrophysiology of Lorcainide and Norlorcainide in the Dog
Electrophysiologic effects of intravenous lorcainide and its major metabolite, norlorcainide, were examined in 18 anesthetized… 
Review
1984
Review
1984
Clinical Pharmacokinetics of the Newer Antiarrhythmic Agents
SummaryThis article reviews clinical pharmacokinetic data on 8 new antiarrhythmic agents. Some of these drugs have been studied… 
Review
1984
Review
1984
Lorcainide. A preliminary review of its pharmacodynamic properties and therapeutic efficacy.
Lorcainide is a type I antiarrhythmic drug of the local anesthetic type. It can be given either intravenously or orally, and its… 
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1984
1984
Pharmacodynamics of the initiation of antiarrhythmic therapy with lorcainide.
Lorcainide is an antiarrhythmic drug with unusual pharmacokinetics and an active metabolite, norlorcainide, which complicate oral… 
1984
1984
Pharmacology of lorcainide.
  • D. Keefe
  • The American journal of cardiology
  • 1984
  • Corpus ID: 37543710
Lorcainide is a new type 1 antiarrhythmic drug that is well absorbed orally, with bioavailability increasing with both dose and… 
1983
1983
Lorcainide disposition kinetics in arrhythmia patients
Lorcainide disposition kinetics were studied after intravenous and oral administration to patients with ventricular arrhythmias… 
1983
1983
Comparison of the electrophysiologic effects of intravenous and oral lorcainide in patients with recurrent ventricular tachycardia.
The electrophysiologic effects of intravenous lorcainide (2.2 mg/kg) in 10 patients were compared with the electrophysiologic… 
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1982
1982
Randomized double-blind placebo controlled crossover trial documenting oral lorcainide efficacy in suppression of symptomatic ventricular tachyarrhythmias.
Lorcainide, a new antiarrhythmic drug, was given to 10 patients with frequent (greater than 1/min) premature ventricular… 
1981
1981
High-performance liquid chromatographic analysis of lorcainide and its active metabolite, norlorcainide, in human plasma.
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