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norlorcainide
National Institutes of Health
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Piperidines
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
1986
1986
Intravenous and oral lorcainide: assessment of central nervous system toxicity and antiarrhythmic efficacy.
S. Vlay
,
G. Mallis
American heart journal
1986
Corpus ID: 32621220
Twenty-eight subjects underwent evaluation of drug toxicity and antiarrhythmic efficacy with oral and intravenous lorcainide…
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1985
1985
Chronic lorcainide therapy for symptomatic premature ventricular complexes: efficacy, pharmacokinetics and evidence for norlorcainide antiarrhythmic effect.
R. Mead
,
D. Keefe
,
R. Kates
,
R. Winkle
The American journal of cardiology
1985
Corpus ID: 40024750
Chronic premature ventricular complexes (PVCs) have been effectively suppressed by oral lorcainide as reported in previous short…
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1984
1984
Comparative Electrophysiology of Lorcainide and Norlorcainide in the Dog
D. Keefe
,
R. Kates
,
R. Winkle
Journal of cardiovascular pharmacology
1984
Corpus ID: 5640096
Electrophysiologic effects of intravenous lorcainide and its major metabolite, norlorcainide, were examined in 18 anesthetized…
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1984
1984
Pharmacodynamics of the initiation of antiarrhythmic therapy with lorcainide.
R. Winkle
,
D. Keefe
,
I. Rodríguez
,
R. Kates
The American journal of cardiology
1984
Corpus ID: 45406071
Lorcainide is an antiarrhythmic drug with unusual pharmacokinetics and an active metabolite, norlorcainide, which complicate oral…
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1984
1984
Pharmacology of lorcainide.
D. Keefe
The American journal of cardiology
1984
Corpus ID: 37543710
Lorcainide is a new type 1 antiarrhythmic drug that is well absorbed orally, with bioavailability increasing with both dose and…
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1983
1983
Lorcainide disposition kinetics in arrhythmia patients
R. Kates
,
D. Keefe
,
R. Winkle
Clinical pharmacology and therapeutics
1983
Corpus ID: 2863101
Lorcainide disposition kinetics were studied after intravenous and oral administration to patients with ventricular arrhythmias…
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1983
1983
Comparison of the electrophysiologic effects of intravenous and oral lorcainide in patients with recurrent ventricular tachycardia.
D. Echt
,
L. Mitchell
,
R. Kates
,
R. Winkle
Circulation
1983
Corpus ID: 14475479
The electrophysiologic effects of intravenous lorcainide (2.2 mg/kg) in 10 patients were compared with the electrophysiologic…
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1982
1982
Randomized double-blind placebo controlled crossover trial documenting oral lorcainide efficacy in suppression of symptomatic ventricular tachyarrhythmias.
D. Keefe
,
F. Peters
,
R. Winkle
American heart journal
1982
Corpus ID: 1729707
Lorcainide, a new antiarrhythmic drug, was given to 10 patients with frequent (greater than 1/min) premature ventricular…
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1982
1982
Rapid and simple method for determination of lorcainide, a new antiarrhythmic drug, and its major metabolite, norlorcainide, by high-performance liquid chromatography.
V. Simon
,
P. Somani
Journal of chromatography
1982
Corpus ID: 38281379
1981
1981
High-performance liquid chromatographic analysis of lorcainide and its active metabolite, norlorcainide, in human plasma.
Y. Yee
,
R. Kates
Journal of chromatography
1981
Corpus ID: 8828644
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