noradrenochrome

Substrate specificity is critically important for enzyme catalysis. In the adrenaline-synthesizing enzyme PNMT… (More)

Aberrant oxidation of norepinephrine (1) via the transient o-quinone has been implicated as a critical pathogenetic mechanism… (More)

The adrenochrome hypothesis of schizophrenia (Hoffer, Osmond and Smythies, 1954), was stimulated by the work of Osmond and… (More)

The catecholamine oxidation process induces cardiotoxicity and neurotoxicity. Catecholamines can oxidize to aminochromes through… (More)

Recent studies have revealed that GSTM1 and M2 of the mu-class glutathione S-transferases catalyze a glutathione conjugate of… (More)

The catecholamines adrenaline, noradrenaline, dopamine, dopa and isoprenaline were oxidized into their respective aminochromes… (More)

o-Quinones are physiological oxidation products of catecholamines that contribute to redox cycling, toxicity and apoptosis, i.e… (More)

One-electron reduction of noradrenochrome catalyzed by NADPH-cytochrome P-450 reductase resulted primarily in the formation of o… (More)

Preparations obtained from various plant sources were analyzed for their effect on the autoxidation of ascorbic acid and… (More)

Characterization of intermediates formed in the noradrenaline oxidation by mushroom tyrosinase and sodium periodate has been… (More)