non-recombinational interstrand cross-link repair
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SUMMARY DNA interstrand crosslinks (ICLs) are extremely cytotoxic, but the mechanism of their repair remains incompletely… Expand During replication‐coupled DNA interstrand crosslink (ICL) repair, the XPF‐ERCC1 endonuclease is required for the incisions that… Expand Histone/protein deacetylases play multiple roles in regulating gene expression and protein activation and stability. Their… Expand DNA interstrand crosslinks (ICLs) are extremely deleterious lesions that are repaired by homologous recombination (HR) through… Expand DNA interstrand crosslinks (ICLs) are highly toxic lesions that stall the replication fork to initiate the repair process during… Expand Background: The structure-specific endonuclease ERCC1-XPF has multiple DNA binding domains. Results: Mutations in two individual… Expand In this review, we focus on the discrepant roles of the DNA repair complex ERCC1/XPF in the prevention of cancer and in the… Expand Although various schemes for interstrand crosslink (ICL) repair incorporate DNA recombination, replication, and double‐strand… Expand DNA interstrand cross-links (ICLs) are the most cytotoxic lesions to eukaryotic genome and are repaired by both homologous… Expand The SNM1 gene of Saccharomyces cerevisiae is specific for repair of DNA interstrand crosslinks (ICLs). We report that the SNM1… Expand