non-recombinational interstrand cross-link repair

Known as: recombination-independent ICL repair, recombination-independent interstrand cross-link repair 
Removal of a DNA interstrand crosslink (a covalent attachment of DNA bases on opposite strands of the DNA) and restoration of the DNA by a mechanism… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1993-2017
02419932017

Papers overview

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2015
2015
DNA interstrand crosslinks (ICLs) are extremely deleterious lesions that are repaired by homologous recombination (HR) through… (More)
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2012
2012
The Fanconi anemia (FA) protein network is necessary for repair of DNA interstrand crosslinks (ICLs), but its control mechanism… (More)
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2012
2012
DNA interstrand crosslinks (ICLs) are highly toxic lesions that stall the replication fork to initiate the repair process during… (More)
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2012
2012
DNA interstrand crosslinks (ICLs) are toxic lesions that block the progression of replication and transcription. CtIP is a… (More)
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2012
2012
ERCC1-XPF is a heterodimeric, structure-specific endonuclease that cleaves single-stranded/double-stranded DNA junctions and has… (More)
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2009
2009
Acetaldehyde (AA) was tested along with two other crosslinking agents: formaldehyde (FA), an inducer of DNA-protein crosslinks… (More)
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2008
2008
Gene targeting via homologous recombination (HR) is an important application in biotechnology and medicine. However, in mammalian… (More)
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2008
2008
DNA interstrand cross-links (ICLs) are mainly repaired by the combined action of nucleotide excision repair and homologous… (More)
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1996
1996
Cyclophosphamide is one of the most active agents in the treatment of medulloblastoma. However, development of resistance to this… (More)
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1994
1994
The human excision repair gene ERCC-1 gene restores normal resistance to UV and mitomycin C in excision repair deficient chinese… (More)
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