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nolatrexed dihydrochloride
Known as:
3,4-Dihydro-2-amino-6-methyl-4-oxy-5-(4-pyridylthio)-quinazoline Dihydrochloride
, 3,4-dihydro-2-amino-6-methyl-4-oxo-5-(4-pyridylthio)quinazoline dihydrochloride
, Nolatrexed Hydrochloride
The dihydrochloride salt of nolatrexed, a water-soluble lipophilic quinazoline folate analog with antineoplastic activity. Nolatrexed occupies the…
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National Institutes of Health
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3 relations
Narrower (2)
AG 337
Thymitaq
Broader (1)
nolatrexed
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2011
2011
Preparation and Quality of Nolatrexed Dihydrochloride Liposomes
Chen Xue
2011
Corpus ID: 137908633
Objective: To prepare nolatrexed dihydrochloride liposmes (NDL)and detect their correlative parameters. Methods: The nolatrexed…
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2008
2008
Synthesis of Nolatrexed Dihydrochloride
Shi Hui-lin
2008
Corpus ID: 102087822
Nolatrexed dihydrochloride dihydrate,a thymidylate synthase inhibitor,was synthesized from 2-bromo-4-nitrotoluene in 8%overall…
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2007
2007
Inhibition Effect of Nolatrexed Dihydrochloride on Transplatation Tumors
Fu Ying-hua
2007
Corpus ID: 76058265
Objective To investigate the inhibition effect against transplatation tumors H22 , EAC and S180 by abdominal cavity injection of…
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2007
2007
Synthesis of nolatrexed dihydrochloride
Zhu Wei-ping
2007
Corpus ID: 100868301
Objective:To improve synthetic process of nolatrexed dihydrochloride.Methods: The target compound was synthesized from 2-bromo-4…
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2007
2007
Preparation of high-purity nolatrexed dihydrochloride dihydrate
张庆文
,
益兵
2007
Corpus ID: 103241867
The invention discloses a method for preparing an IV crystal form of nolatrexed dihydrochloride, which comprises the steps that…
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2005
2005
Expediting Oncology Drug Approvals: The Public Backlash Against the FDA and Opportunities to Reform
Andrew J. Sung
2005
Corpus ID: 74628187
The FDA has made great strides over the past twenty years in loosening drug approval regulations to speed important, life-saving…
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2004
2004
Distribution of nolatrexed dihydrochloride in mice bearing S180 sarcoma and its effect on liver cancer cell lines in vitro
Zhao Ai
2004
Corpus ID: 87635988
OBJECTIVES:To evaluate the anti proliferation effect of nolatrexed dihydrochloride (NLTX) on normal human embryo liver cell Fb…
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2003
2003
Synergistic Anticancer Effect of Sodium Phenylbutyrate Combined with Nolatrexed Dihydrochloride in vitro
Chen Wei-min
2003
Corpus ID: 101571631
To study the interaction between sodium phenylbutyrate (SPB) and nolatrexed dihydrochloride(Nolatrexed) against LoVo cell and…
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2002
2002
Antiproliferative Effect of Nolatrexed Dihydrochloride on Cell Line S-180 in vitro and in vivo
Zhao Ai-guo
2002
Corpus ID: 100474947
The anticancer effect of nolatrexed dihydrochloride on mouse cancer cell line S-180 in vitro and in vivo and the…
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