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nodulisporic acid A
Known as:
nodulisporic acid-A
National Institutes of Health
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2009
2009
Discovery of the development candidate N-tert-butyl nodulisporamide: a safe and efficacious once monthly oral agent for the control of fleas and ticks on companion animals.
P. Meinke
,
S. Colletti
,
+16 authors
W. Shoop
Journal of Medicinal Chemistry
2009
Corpus ID: 24623459
Nodulisporic acid A (1) is a structurally complex fungal metabolite that exhibits systemic efficacy against fleas via modulation…
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Review
2002
Review
2002
Nodulisporic acid: its chemistry and biology.
P. Meinke
,
McHardy M. Smith
,
W. Shoop
Current Topics in Medicinal Chemistry
2002
Corpus ID: 30790163
The discovery of the natural product nodulisporic acid A (NsA A) and its potent, systemic insecticidal activity at Merck Research…
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2002
2002
Synthesis of side chain truncated 3"-aldehyde, 3"-carboxylic acid, and 1"-aldehyde from nodulisporic acid A.
P. Chakravarty
,
S. Tyagarajan
,
+5 authors
P. Meinke
Organic Letters
2002
Corpus ID: 1357445
An efficient synthesis of the truncated 3"-aldehyde (3) from nodulisporic acid A (1) under mild conditions is described. Further…
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2002
2002
Nodulisporic acid B, B1, and B2: a series of 1'-deoxy-nodulisporic acids from Nodulisporium sp.
J. Ondeyka
,
Arlene Dahl-Roshak
,
+5 authors
Sheo B. Singh
Bioorganic & Medicinal Chemistry Letters
2002
Corpus ID: 29447382
2001
2001
Systemic efficacy of nodulisporic acid against fleas on dogs.
W. Shoop
,
L. Gregory
,
+5 authors
D. Schmatz
Journal of Parasitology
2001
Corpus ID: 25135421
Nodulisporic acid A (NSA) is a novel natural product from a new structural class that was shown previously to have insecticidal…
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2001
2001
Synthesis of nodulisporic acid 2' '-oxazoles and 2' '-thiazoles.
R. Berger
,
W. Shoop
,
+9 authors
S. Colletti
Organic Letters
2001
Corpus ID: 39429195
[reaction--see text] The semisynthetic conversion of nodulisporic acid A (1) into a set of three heterocyclic side chain…
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2001
2001
SYSTEMIC EFFICACY OF NODULISPORAMIDES AGAINST FLEAS ON DOGS
W. Shoop
,
M. Zakson-Aiken
,
+7 authors
D. Schmatz
Journal of Parasitology
2001
Corpus ID: 36179672
Nodulisporic acid A (NSA) has been shown previously to be safe in dogs and to deliver >90% flea control for 4 days following a…
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2000
2000
Chemical modification of nodulisporic acid A: preliminary structure-activity relationships.
P. Meinke
,
M. B. Ayer
,
+11 authors
M. Fisher
Bioorganic & Medicinal Chemistry Letters
2000
Corpus ID: 12871248
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