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nodulisporic acid A

Known as: nodulisporic acid-A 
National Institutes of Health

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2009
2009
Discovery of the development candidate N-tert-butyl nodulisporamide: a safe and efficacious once monthly oral agent for the control of fleas and ticks on companion animals.
Nodulisporic acid A (1) is a structurally complex fungal metabolite that exhibits systemic efficacy against fleas via modulation… 
Review
2002
Review
2002
Nodulisporic acid: its chemistry and biology.
The discovery of the natural product nodulisporic acid A (NsA A) and its potent, systemic insecticidal activity at Merck Research… 
2002
2002
Synthesis of side chain truncated 3"-aldehyde, 3"-carboxylic acid, and 1"-aldehyde from nodulisporic acid A.
An efficient synthesis of the truncated 3"-aldehyde (3) from nodulisporic acid A (1) under mild conditions is described. Further… 
2002
2002
Nodulisporic acid B, B1, and B2: a series of 1'-deoxy-nodulisporic acids from Nodulisporium sp.
2001
2001
Systemic efficacy of nodulisporic acid against fleas on dogs.
Nodulisporic acid A (NSA) is a novel natural product from a new structural class that was shown previously to have insecticidal… 
2001
2001
Synthesis of nodulisporic acid 2' '-oxazoles and 2' '-thiazoles.
[reaction--see text] The semisynthetic conversion of nodulisporic acid A (1) into a set of three heterocyclic side chain… 
2001
2001
SYSTEMIC EFFICACY OF NODULISPORAMIDES AGAINST FLEAS ON DOGS
Nodulisporic acid A (NSA) has been shown previously to be safe in dogs and to deliver >90% flea control for 4 days following a… 
2000
2000
Chemical modification of nodulisporic acid A: preliminary structure-activity relationships.
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